In vivo, tibial loading in mice is increasingly used to study bone adaptation and
mechanotransduction. To achieve standardized and defined experimental conditions …

Supercritical CO 2 techniques are promising technologies for developing products that can
be useful for biomedical engineering. However, the obtained products (aerogels, foams …

Decades of research have demonstrated that physical stress (PS) stimulates bone
remodeling and affects bone structure and function through complex mechanotransduction …

The skeleton's osteogenic response to mechanical loading can be affected by loading
duration and rest insertion during a series of loading events. Prior animal loading studies …

The skeleton accommodates changes in mechanical environments by increasing bone
mass under increased loads and decreasing bone mass under disuse. However, little is …

Although mechanical stimulation is considered a promising approach to accelerate implant
integration, our understanding of load-driven bone formation and resorption around implants …

The conceptual model of the mechanostat proposed by Harold Frost in 1983 is among the
most significant contributions to musculoskeletal research today. This model states that bone …

Bone is one of the most common and most dangerous sites for metastatic growth across
cancer types, and bone metastasis remains incurable. Unfortunately, the processes by …

In a globally aging society, synthetic bone blocks are in increasing demand. An ideal
synthetic bone block fuses early with bone and is replaced with new bone at a suitable …

Many nontraumatic fractures seen clinically in patients with metabolic bone disorders or on
antiresorptive treatment show an increased incidence of microdamage accumulation and …