While red blood cell (RBC) transfusion is the most common medical intervention in
hospitalized patients, as with any therapeutic, it is not without risk. Allogeneic RBC exposure …

The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

The American Society for Apheresis (ASFA) JCA Special Issue Writing Committee is
charged with reviewing, updating and categorizating indications for therapeutic apheresis …

Red blood cell (RBC) transfusion is a key treatment of patients with sickle cell disease (SCD)
but remains complicated by RBC immunization. In the present study, we evaluated the …

Transfusions can be a life-saving treatment of patients with sickle-cell disease (SCD).
However, availability of matched units can be limiting because of distinctive blood group …

In the 100 years since sickle cell anemia (SCA) was first described in the medical literature,
studies of its molecular and pathophysiological basis have been at the vanguard of scientific …

Anti‐D (‐RH 1) of the Rh blood group system is clinically important as it causes haemolytic
transfusion reactions and haemolytic disease of the fetus and newborn. Although most …

Sickle cell disease (SCD) is the most important hemoglobinopathy worldwide in terms of
frequency and social impact, recently recognized as a global public health problem by the …

BACKGROUND RBC transfusion effectiveness varies due to donor, component, and
recipient factors. Prior studies identified characteristics associated with variation in …

Sickle cell disease (SCD) is an inherited blood disorder characterized by sickled red blood
cells (RBCs), which are more sensitive to haemolysis and can contribute to disease …