Proteases are classified into six distinct classes (cysteine, serine, threonine, aspartic,
glutamic, and metalloproteases) on the basis of catalytic mechanism. The cellular control of …

Hemorrhagic stroke is a life-threatening disease characterized by a sudden rupture of
cerebral blood vessels, and cell death is widely believed to occur after exposure to blood …

Therapeutic treatment options for central nervous system diseases are greatly limited by the
blood-brain barrier (BBB). Focused ultrasound (FUS), in conjunction with circulating …

Traumatic brain injury (TBI) impacts over 3.17 million Americans. Management of
hemorrhage and coagulation caused by vascular disruption after TBI is critical for the …

Neural progenitor cells (NPCs) of the subventricular zone proliferate in response to ischemic
stroke in the adult mouse brain. Newly generated cells have been considered to influence …

Ischemic brain injury triggers neuronal cell death by apoptosis via caspase activation and by
necroptosis through activation of the receptor-interacting protein kinases (RIPK) associated …

We have previously reported that mild TBI created by focal left-side cranial blast in mice
produces widespread axonal injury, microglial activation, and a variety of functional deficits …

Spontaneous recovery after a stroke accounts for a significant part of the neurological
recovery in patients. However limited, the spontaneous recovery is mechanistically driven by …

Based on the review of the literature, perinatal inflammation often induced by infection is the
only consistent independent risk factor of neonatal arterial ischemic stroke (NAIS) …

Awareness and research on epilepsy‐related deaths (ERD), in particular Sudden
Unexpected Death in Epilepsy (SUDEP), have exponentially increased over the last two …