When replication forks encounter template lesions, one result is lesion skipping, where the
stalled DNA polymerase transiently stalls, disengages, and then reinitiates downstream to …

The single‐stranded DNA binding protein (SSB) is essential to all aspects of DNA
metabolism in bacteria. This protein performs two distinct, but closely intertwined and …

Collisions between cellular DNA replication machinery (replisomes) and damaged DNA or
immovable protein complexes can dissociate replisomes before the completion of …

We have investigated the structural, biochemical and cellular roles of the two single-
stranded (ss) DNA-binding proteins from Bacillus subtilis, SsbA and SsbB. During …

In bacteria, one type of homologous-recombination-based DNA-repair pathway involves
RecFOR proteins that bind at the junction between single-stranded (ss) and double …

Escherichia coli single stranded (ss) DNA binding protein (SSB) plays essential roles in
DNA maintenance. It binds ssDNA with high affinity through its N-terminal DNA binding core …

The gut microbiome is highly involved in numerous aspects of host physiology, from energy
harvest to stress response, and can confer many benefits to the host. The gut microbiome …

DNA replication forks stall at least once per cell cycle in Escherichia coli. DNA replication
must be restarted if the cell is to survive. Restart is a multi-step process requiring the …

Tetrameric single-stranded (ss) DNA-binding proteins (SSBs) stabilize ssDNA intermediates
formed during genome maintenance reactions in Bacteria. SSBs also recruit proteins …

Frequent collisions between cellular DNA replication complexes (replisomes) and obstacles
such as damaged DNA or frozen protein complexes make DNA replication fork progression …