Recent development in hydrophilic interaction liquid chromatography stationary materials for glycopeptide analysis

Z Liu, M Xu, W Zhang, X Miao, PG Wang, S Li… - Analytical …, 2022 - pubs.rsc.org
Protein glycosylation is one of the most important post-translational modifications, and
aberrant glycosylation is associated with the occurrence and development of diseases …

Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis

LR Conroy, HA Clarke, DB Allison, SS Valenca… - Nature …, 2023 - nature.com
Matrix assisted laser desorption/ionization imaging has greatly improved our understanding
of spatial biology, however a robust bioinformatic pipeline for data analysis is lacking. Here …

Multiply-mesoporous hydrophilic titanium dioxide nanohybrid for the highly-performed enrichment of N-glycopeptides from human serum

Y Lin, C Du, H Ying, Y Zhou, F Kong, H Zhao… - Analytica Chimica Acta, 2024 - Elsevier
N-glycopeptide is considered as one of significant biomarkers which provide guidance for
the diagnosis and drug design of diseases. However, the direct analysis of N-glycopeptides …

The Complex Immunological Alterations in Patients with Type 2 Diabetes Mellitus on Hemodialysis

MF Trandafir, OI Savu, M Gheorghiu - Journal of Clinical Medicine, 2024 - mdpi.com
It is widely known that diabetes mellitus negatively impacts both the innate immunity (the
inflammatory response) and the acquired immunity (the humoral and cellular immune …

Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma

Z Li, N Zhang, Z Dong, X Wang, J Zhou, J Gao… - Cell Communication and …, 2024 - Springer
Background Hepatocellular carcinoma (HCC) ranks as the third most common cause of
cancer related death globally, representing a substantial challenge to global healthcare …

Cisplatin induces acute kidney injury by downregulating miR‐30e‐5p that targets Galnt3 to activate the AMPK signaling pathway

W Mao, L Zhang, Y Wang, S Sun, J Wu… - Environmental …, 2024 - Wiley Online Library
Cisplatin nephrotoxicity is an etiological factor for acute kidney injury (AKI). MicroRNA
(miRNA) expression is dysregulated in cisplatin‐induced AKI (cAKI) although the underlying …

GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling …

L Guo, Y Wang, S Li, L Zhou, D Li - Cellular Signalling, 2022 - Elsevier
Vascular calcification (VC) acts as a notable risk factor in the cardiovascular system.
Disorder of phosphorus (Pi) metabolism promotes VC. Recent findings show that …

IgG glycopeptide enrichment using hydrophilic interaction chromatography-based solid-phase extraction on an aminopropyl column

K Molnarova, M Chobotova, P Kozlik - Analytical and Bioanalytical …, 2024 - Springer
The sample preparation step is pivotal in glycoproteomic analysis. An effective approach in
glycoprotein sample preparation involves enriching glycopeptides by solid-phase extraction …

Antidiabetic, Antihyperlipidemic, Antioxidant Effects and Regulation of miRNA Expression by Dianthus orientalis Adams Extract in Diabetic rat Model

VA Ahmed, HS Rahman… - Natural Product …, 2024 - journals.sagepub.com
Background: The Mediterranean area is a diversity center for the genus Dianthus. However,
species belonging to this genus, including Dianthus orientalis Adams (DOA), have not been …

Hydrofilná interakčná kvapalinová chromatografia v analýze intaktných glykopeptidov

K Molnárová - 2024 - dspace.cuni.cz
Analýza glykoproteínov predstavuje obrovskú výzvu v rámci glykoproteomiky, a to hlavne
kvôli makro-a mikroheterogenite glykozylácie. Hydrofilná interakčná kvapalinová …