Sexuality is important for most cisgender as well as transgender persons and is an essential
aspect of quality of life. For both the patient and their clinicians, managing gender dysphoria …

Androgens are potent drugs requiring prescription for valid medical indications but are
misused for invalid, unproven, or off-label reasons as well as being abused without …

Abstract Objective To update the “Testosterone Therapy in Men With Androgen Deficiency
Syndromes” guideline published in 2010. Participants The participants include an Endocrine …

The use of opioids is becoming a global epidemic, leading to a rise in the occurrence and
recognition of the effects of opioid drugs on the endocrine system. Nonetheless, opioid …

Background Hypogonadism is prevalent during opioid treatment, but the effect of
testosterone replacement treatment (TRT) on body composition, pain perception, and …

Background Opioid analgesics have been widely used to relieve chronic pain conditions;
however, a connection between opioid analgesic administration and increased susceptibility …

Introduction Over the last several decades, the opioid epidemic has become a national
crisis, largely spurred by the spike in the use of prescription painkillers. With the epidemic …

Objective: Opioid-induced adrenal insufficiency (OIAI) may develop in patients treated with
chronic opioids due to suppression of the hypothalamic-pituitary-adrenal axis. Our objective …

Introduction The symptoms of low testosterone frequently overlap with psychiatric complaints
including depression and fatigue. Testosterone repletion has been shown to improve mood …

Objective To systematically review evidence addressing the efficacy of testosterone
replacement therapy (TRT) and opioid tapering for opioid-induced hypogonadism among …