Borrowing hydrogen is a process that is used to diversify the synthetic utility of commodity
alcohols. A catalyst first oxidizes an alcohol by removing hydrogen to form a reactive …

Direct substitution of readily available alcohols is recognized as a key research area in
green chemical synthesis. Starting from simple racemic secondary alcohols, the …

Since its advent two decades ago, asymmetric organo/transition-metal combined catalysis
(AOMC), including cooperative catalysis and relay catalysis, has leveraged redistribution of …

In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable
assembled a list of key green chemistry research areas to both identify transformations that …

Borrowing hydrogen or the hydrogen autotransfer amination is a powerful approach to
create single C–N bonds, starting from stable and readily available substrates: amines and …

An unprecedented hydroalkylation of racemic allylic alcohols and racemic ketimine esters
enabled by Cu/Ru relay catalysis has been developed via merging the ruthenium‐catalyzed …

Stereoconvergent catalysis is an important subset of asymmetric synthesis that
encompasses stereoablative transformations, dynamic kinetic resolutions, and dynamic …

We present an enantioconvergent access to chiral N-heterocycles directly from simple
racemic diols and primary amines, through a highly economical borrowing hydrogen …

In this review, we consider the main processes for the asymmetric transfer hydrogenation of
ketones from 2008 up today. The most effective organometallic compounds (derived from …

Figure 73: The proposed catalyst/substrate interaction shown in Figure 73 corresponds to
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …