Viruses and intracellular bacterial pathogens (IBPs) have in common the need of suitable
host cells for efficient replication and proliferation during infection. In human infections, the …

In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …

Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …

Persistence has evolved as a potent survival strategy to overcome adverse environmental
conditions. This capability is common to almost all bacteria, including all human bacterial …

Antimicrobial resistance is at an all‐time high and new drugs are required to overcome this
crisis. Traditional approaches to drug discovery have failed to produce novel classes of …

Glycerol and glycerol-containing compounds such as lipids belong to the most abundant
organic compounds that may serve as nutrient for many bacteria. For the cell wall-less …

Obligate intracellular bacteria such as Chlamydia trachomatis undergo a complex
developmental cycle between infectious, non-replicative elementary-body and non …

Metabolic pathways are now considered as intrinsic virulence attributes of pathogenic
bacteria and thus represent potential targets for antibacterial strategies. Here we focused on …

The host is a nutrient-rich niche for microbial pathogens, but one that comes with obstacles
and challenges. Many intracellular pathogens like Legionella pneumophila, Coxiella …

Intracellular bacterial pathogens (IBPs) invade and replicate in different cell types including
immune cells, in particular of the innate immune system (IIS) during infection in the acute …