Hepatocellular carcinoma: new developments

P Ganesan, LM Kulik - Clinics in liver disease, 2023 - liver.theclinics.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide and a leading cause of death in cirrhosis. The prognosis in HCC is poor, with …

Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy

AG Singal, F Kanwal, JM Llovet - Nature reviews Clinical oncology, 2023 - nature.com
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …

AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

AG Singal, JM Llovet, M Yarchoan, N Mehta… - Hepatology, 2023 - journals.lww.com
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …

Epidemiology and surveillance for hepatocellular carcinoma: New trends

AG Singal, P Lampertico, P Nahon - Journal of hepatology, 2020 - Elsevier
The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although
its incidence and mortality are rapidly rising in the United States and Europe. With the …

New advances in the diagnosis and management of hepatocellular carcinoma

JD Yang, JK Heimbach - Bmj, 2020 - bmj.com
Hepatocellular carcinoma is one of the leading causes of cancer related death in the world.
Biannual surveillance for the disease in patients with cirrhosis and in high risk carriers of …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American Association for the Study of Liver Diseases

JA Marrero, LM Kulik, CB Sirlin, AX Zhu, RS Finn… - Hepatology, 2018 - journals.lww.com
This guidance provides a data-supported approach to the diagnosis, staging, and treatment
of patients diagnosed with hepatocellular carcinoma (HCC). A guidance document is …

Nonalcoholic steatohepatitis is the fastest growing cause of hepatocellular carcinoma in liver transplant candidates

Z Younossi, M Stepanova, JP Ong, IM Jacobson… - Clinical …, 2019 - Elsevier
Background & Aims Although hepatitis B and C have been the main drivers of hepatocellular
carcinoma (HCC), nonalcoholic steatohepatitis (NASH) has recently become an important …

Surveillance imaging and alpha fetoprotein for early detection of hepatocellular carcinoma in patients with cirrhosis: a meta-analysis

K Tzartzeva, J Obi, NE Rich, ND Parikh, JA Marrero… - Gastroenterology, 2018 - Elsevier
Background & Aims Society guidelines differ in their recommendations for surveillance to
detect early-stage hepatocellular carcinoma (HCC) in patients with cirrhosis. We compared …

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

N Fujiwara, SL Friedman, N Goossens, Y Hoshida - Journal of hepatology, 2018 - Elsevier
Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies,
are at a high risk of developing hepatocellular carcinoma (HCC). Even after complete HCC …