This review focuses on the type A cytochrome c oxidases (C c O), which are found in all
mitochondria and also in several aerobic bacteria. C c O catalyzes the respiratory reduction …

On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Cytochrome c oxidase (CcO), the terminal oxidase of cell respiration, reduces molecular
oxygen (O2) in a reaction that is coupled with proton pumping. Since the discovery of this …

In the final steps of energy conservation in aerobic organisms, free energy from electron
transfer through the respiratory chain is transduced into a proton electrochemical gradient …

The crystal structure of bovine heart cytochrome c oxidase at 2.8 Å resolution with an R
value of 19.9 percent reveals 13 subunits, each different from the other, five phosphatidyl …

Spatially well-organized electron-transfer reactions in a series of membrane-bound redox
proteins form the basis for energy conservation in both photosynthesis and respiration. The …

Cellular respiration has a long research history at the interface between biology, chemistry,
and physics. Research in this field spans the entire range from fundamental mechanistic and …

Proton channels exist in a wide variety of membrane proteins where they transport protons
rapidly and efficiently. Usually the proton pathway is formed mainly by water molecules …

▪ Abstract Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the
energy made available from electron transfer reactions to transport protons across the inner …

The crystal structures of cytochrome c oxidase from both bovine and Paracoccus
denitrificans reveal two putative proton input channels that connect the heme-copper center …