Alternative animal models of aging research
S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
Maturation in Atlantic salmon (Salmo salar, Salmonidae): a synthesis of ecological, genetic, and molecular processes
Over the past decades, Atlantic salmon (Salmo salar, Salmonidae) has emerged as a model
system for sexual maturation research, owing to the high diversity of life history strategies …
system for sexual maturation research, owing to the high diversity of life history strategies …
Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates
INTRODUCTION The ability to regenerate tissues lost to damage or disease is widely but
nonuniformly distributed in vertebrates. Some animals such as teleost fishes can regenerate …
nonuniformly distributed in vertebrates. Some animals such as teleost fishes can regenerate …
Animal life history is shaped by the pace of life and the distribution of age-specific mortality and reproduction
Animals exhibit an extraordinary diversity of life history strategies. These realized
combinations of survival, development and reproduction are predicted to be constrained by …
combinations of survival, development and reproduction are predicted to be constrained by …
Relaxed selection limits lifespan by increasing mutation load
R Cui, T Medeiros, D Willemsen, LNM Iasi, GE Collier… - Cell, 2019 - cell.com
To uncover the selective forces shaping life-history trait evolution across species, we
investigate the genomic basis underlying adaptations to seasonal habitat desiccation in …
investigate the genomic basis underlying adaptations to seasonal habitat desiccation in …
[HTML][HTML] Turquoise killifish: A natural model of age-dependent brain degeneration
DEM de Bakker, DR Valenzano - Ageing Research Reviews, 2023 - Elsevier
Turquoise killifish (Nothobranchius furzeri) are naturally short-lived vertebrates that display a
wide range of spontaneous age-related changes, including onset of cancer, reduced …
wide range of spontaneous age-related changes, including onset of cancer, reduced …
Nothobranchius furzeri, an 'instant' fish from an ephemeral habitat
M Reichard, M Polačik - Elife, 2019 - elifesciences.org
The turquoise killifish, Nothobranchius furzeri, is a promising vertebrate model in ageing
research and an emerging model organism in genomics, regenerative medicine …
research and an emerging model organism in genomics, regenerative medicine …
[HTML][HTML] Production of common carp donor-derived offspring from goldfish surrogate broodstock
Common carp (Cyprinus carpio) is the fourth most-produced species in worldwide
aquaculture. Significant efforts are invested in breeding and preservation of genetic integrity …
aquaculture. Significant efforts are invested in breeding and preservation of genetic integrity …
A scalable and tunable platform for functional interrogation of peptide hormones in fish
Pituitary hormones play a central role in shaping vertebrate life history events, including
growth, reproduction, metabolism, and aging. The regulation of these traits often requires …
growth, reproduction, metabolism, and aging. The regulation of these traits often requires …
The killifish germline regulates longevity and somatic repair in a sex-specific manner
Classical evolutionary theories propose tradeoffs among reproduction, damage repair and
lifespan. However, the specific role of the germline in shaping vertebrate aging remains …
lifespan. However, the specific role of the germline in shaping vertebrate aging remains …