The mammalian bombesin receptor family comprises three G protein-coupled heptahelical
receptors: the neuromedin B (NMB) receptor (BB1), the gastrin-releasing peptide (GRP) …

The mammalian bombesin (BB)-like peptide gastrin-releasing peptide (GRP) stimulates cell
proliferation, displays a range of neuroendocrine activities, and acts as a growth factor in the …

The autocrine hypothesis proposes that a cell produces and secretes a hormone-like
substance that can interact with specific membrane receptors on its surface to induce effects …

Numerous peptides appear to be neurotransmitter candidates in the brain. Some, such as
the opioid peptide enkephalins, neurotensin, and substance P, were first isolated from the …

Aptamer-based proteomics revealed differentially abundant proteins in Alzheimer's disease
(AD) brains in the Baltimore Longitudinal Study of Aging and Religious Orders Study (mean …

" Small cells" or" oat cells" characterize a virulent form of lung cancer and share many
biochemical properties with peptide-secreting neurones. The neuropeptide bombesin is …

Specific cholecystokinin binding sites in particulate fractions of rat brain were measured with
iodine 125-labeled Bolton-Hunter cholecystokinin, a cholecystokinin analog that has full …

Recent binding studies in the central nervous system and other tissues provide evidence
that the mammalian bombesin-like peptides, gastrin-releasing peptide (CRP) and …

Biochemical investigation of receptors for neurotransmitters and drugs in the brain has been
one of the most active areas of molecular neuroscience during the past decade. This work …

Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. At nanomolar concentrations
the peptide markedly enhances the ability of fresh serum to stimulate DNA synthesis in …