Age-related changes in pharmacokinetics

S Shi, U Klotz - Current drug metabolism, 2011 - ingentaconnect.com
Ageing is characterized by a progressive decline in the functional reserve of multiple organs
and systems, which can influence drug disposition. In addition, comorbidity and …

Studies to reduce unnecessary medication use in frail older adults: a systematic review

J Tjia, SJ Velten, C Parsons, S Valluri, BA Briesacher - Drugs & aging, 2013 - Springer
Background Overuse of unnecessary medications in frail older adults with limited life
expectancy remains an understudied challenge. Objective To identify intervention studies …

Risk factors for hospital readmission in older adults within 30 days of discharge–a comparative retrospective study

M Glans, A Kragh Ekstam, U Jakobsson, Å Bondesson… - BMC geriatrics, 2020 - Springer
Background The area of hospital readmission in older adults within 30 days of discharge is
extensively researched but few studies look at the whole process. In this study we …

Medication reviews by clinical pharmacists at hospitals lead to improved patient outcomes: a systematic review

T Graabæk, LJ Kjeldsen - Basic & clinical pharmacology & …, 2013 - Wiley Online Library
Suboptimal medication use may lead to morbidity, mortality and increased costs. To reduce
unnecessary patient harm, medicines management including medication reviews can be …

Impact of the Lund Integrated Medicines Management (LIMM) model on medication appropriateness and drug-related hospital revisits

LM Hellström, Å Bondesson, P Höglund… - European journal of …, 2011 - Springer
Purpose To examine the impact of systematic medication reconciliations upon hospital
admission and of a medication review while in hospital on the number of inappropriate …

Errors in medication history at hospital admission: prevalence and predicting factors

LM Hellström, Å Bondesson, P Höglund… - BMC clinical …, 2012 - Springer
Background An accurate medication list at hospital admission is essential for the evaluation
and further treatment of patients. The objective of this study was to describe the frequency …

Improved quality in the hospital discharge summary reduces medication errors—LIMM: Landskrona Integrated Medicines Management

A Bergkvist, P Midlöv, P Höglund, L Larsson… - European journal of …, 2009 - Springer
Purpose We have developed a model for integrated medicines management, including tools
and activities for medication reconciliation and medication review. In this study, we focus on …

Effects of medication reviews on use of potentially inappropriate medications in elderly patients; a cross-sectional study in Swedish primary care

C Lenander, Å Bondesson, N Viberg… - BMC health services …, 2018 - Springer
Background Drug use among the elderly population is generally extensive and the use of
potentially inappropriate medications (PIMs) is common, which increases the risk for drug …

The impact of a structured pharmacist intervention on the appropriateness of prescribing in older hospitalized patients

D O'Sullivan, D O'Mahony, MN O'Connor, P Gallagher… - Drugs & aging, 2014 - Springer
Background Throughout the literature, drug-related problems (DRPs), such as medication
reconciliation issues and potentially inappropriate prescribing, have been reported to be …

Improving the appropriateness of prescribing in older patients: a systematic review and meta-analysis of pharmacists' interventions in secondary care

KA Walsh, D O'Riordan, PM Kearney… - Age and …, 2016 - academic.oup.com
Introduction: potentially inappropriate prescribing (PIP) in older hospitalised patients, and in
particular those with dementia, is associated with poorer health outcomes. PIP reduction is …