With continued smoking of tobacco products and expanded use of nicotine delivery devices
worldwide, understanding the impact of smoking and vaping on respiratory health remains a …

Previous evidence showed that administration of d-galactose (d-gal) increased ROS
production and resulted in impairment of cholinergic system. Troxerutin, a natural …

Although nicotinic acetylcholine receptors (nAChRs) are commonly associated with neurons
in the brain and periphery, recent data indicate that they are also expressed in non-neuronal …

Diseases such as asthma are exacerbated by inflammation, cigarette smoke and even
nicotine delivery devices such as e-cigarettes. However, there is currently little information …

Neurotrophins (NTs) are four small proteins produced by both neuronal and non-neuronal
cells; they include nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) …

Previous studies have shown that molecules of the taste transduction pathway may serve as
biochemical markers for chemoreceptive cells in respiratory and gastrointestinal tracts. In …

Exposure to cigarette smoke and e-cigarettes, with nicotine as the active constituent,
contributes to increased health risks associated with asthma. Nicotine exerts its functional …

Amyotrophic lateral sclerosis (ALS) causes progressive motor neuron degeneration,
paralysis and death by ventilatory failure. In rodent ALS models: 1) breathing capacity is …

Rostral ventral medulla (RVM) contains significant numbers of local GABAergic neurons
which may subserve respiratory chemosensory and baroreceptor reflexes. Nicotinic …

AIMS: The ability to sense the bitter taste of nicotine is an important component of addiction
to, and withdrawal from, cigarette smoking. α-Gustducin and phospholipase C-β2 (PLC-β2) …