The illicit recreational drug of abuse, γ-hydroxybutyrate (GHB) is a potent central nervous
system depressant and is often encountered during forensic investigations of living and …

GHB is used therapeutically and recreationally, although the precise mechanism of action
responsible for its different behavioral effects is not entirely clear. The purpose of this review …

Slow-wave sleep (SWS) modulation in rodent models of Alzheimer's disease alters
extracellular amyloid burden. In Parkinson's disease (PD), SWS appears to be closely linked …

OBJECTIVES: Gamma-hydroxybutyrate (GHB) is currently authorized by the European
Medicines Agency (EMA) to treat narcolepsy with cataplexy in adults, and by the Food and …

The global north is facing an unprecedented rise in the prevalence of neurodegenerative
diseases. The increasing incidence of Parkinson's disease is being referred to as a …

Sleep spindles are key electroencephalogram (EEG) oscillatory events that occur during
non-rapid eye movement (NREM) sleep. Deficits in sleep spindles are present in …

Study Objectives: To assess the efficacy and safety of sodium oxybate (SXB) in narcolepsy-
cataplexy patients. Design: Systematic review and meta-analysis. Patients: Adults with …

Designer drugs belong to a group of legally or illegally produced substances that are
structurally and pharmacologically very similar to illicit drugs. In the past, designer drugs …

Study Objectives: To evaluate the effect of type 1 narcolepsy (NT1) on anthropometric and
endocrine features in childhood/adolescence, focusing on patterns and correlates of weight …

Gamma-hydroxybutyrate (GHB) is a short chain fatty acid endogenously produced within the
central nervous system (CNS) and acts as a precursor and metabolite of the inhibitory …