Fetal alcohol spectrum disorders

S Popova, ME Charness, L Burd, A Crawford… - Nature reviews Disease …, 2023 - nature.com
Alcohol readily crosses the placenta and may disrupt fetal development. Harm from prenatal
alcohol exposure (PAE) is determined by the dose, pattern, timing and duration of exposure …

Hazardous drinking and alcohol use disorders

J MacKillop, R Agabio, SW Feldstein Ewing… - Nature Reviews …, 2022 - nature.com
Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous
drinking, defined by quantity and frequency of consumption, is associated with acute and …

Genetic influences on fetal alcohol spectrum disorder

D Sambo, D Goldman - Genes, 2023 - mdpi.com
Fetal alcohol spectrum disorder (FASD) encompasses the range of deleterious outcomes of
prenatal alcohol exposure (PAE) in the affected offspring, including developmental delay …

Fetal alcohol spectrum disorders: Genetic and epigenetic mechanisms

N Kaminen‐Ahola - Prenatal diagnosis, 2020 - Wiley Online Library
Fetal alcohol spectrum disorders (FASD) are a consequence of prenatal alcohol exposure
(PAE). The etiology of the complex FASD phenotype with growth deficit, birth defects, and …

Modeling the enigma of complex disease etiology

LM Schriml, R Lichenstein, K Bisordi, C Bearer… - Journal of Translational …, 2023 - Springer
Background Complex diseases often present as a diagnosis riddle, further complicated by
the combination of multiple phenotypes and diseases as features of other diseases. With the …

[HTML][HTML] Comparison of the 4-Digit Code, Canadian 2015, Australian 2016 and Hoyme 2016 fetal alcohol spectrum disorder diagnostic guidelines

SJA Hemingway, JM Bledsoe, A Brooks… - Advances in pediatric …, 2019 - ncbi.nlm.nih.gov
Background: As clinicians strive to achieve consensus worldwide on how best to diagnose
fetal alcohol spectrum disorders (FASD), the most recent FASD diagnostic systems show …

Aggressive behaviour and violence in children and adolescents with FASD: a synthesizing review

JJ Joseph, M Mela, J Pei - Clinical psychology review, 2022 - Elsevier
Abstract Interpretation and response to behaviour is predicated on understanding. However,
our present understanding of aggressive behaviour, especially for complex and vulnerable …

Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders

HM Hwang, S Yamashita, Y Matsumoto, M Ito… - Molecular …, 2024 - nature.com
A hallmark of fetal alcohol spectrum disorders (FASD) is neurobehavioral deficits that still do
not have effective treatment. Here, we present that reduction of Apolipoprotein E (APOE) is …

Gene–environment interactions in the pathogenesis of common craniofacial anomalies

S Fitriasari, PA Trainor - Current Topics in Developmental Biology, 2023 - Elsevier
Craniofacial anomalies often exhibit phenotype variability and non-mendelian inheritance
due to their multifactorial origin, involving both genetic and environmental factors. A …

Introduction to The Routledge Handbook of Social Work and Addictive Behaviors

AL Begun, MM Murray - The Routledge Handbook of Social Work …, 2020 - taylorfrancis.com
Addictive behaviors, such as substance misuse, gambling, and internet gaming, and their
attendant problems are associated with significant difficulties for individuals, families …