Although the structure and composition of collagen have been studied by polarized light
microscopy since the early 19th century, many studies and reviews have paid little or no …

Due to the restricted intrinsic capacity of resident chondrocytes to regenerate the lost
cartilage postinjury, stem cell‐based therapies have been proposed as a novel therapeutic …

Objective The efficacy and safety of BST-CarGel®, a chitosan scaffold for cartilage repair
was compared with microfracture alone at 1 year during a multicenter randomized controlled …

Cartilage repair strategies aim to resurface a lesion with osteochondral tissue resembling
native cartilage, but a variety of repair tissues are usually observed. Histology is an …

We present polarization-sensitive Fourier ptychographic microscopy (PS-FPM) capable of
generating high-resolution birefringence images of optically anisotropic specimens over a …

Abstract Background Prostate cancer (PCa) is among the most commonly diagnosed
malignancies in men. Although 5-year survival in patients with localised disease reaches …

OBJECTIVE: This study characterizes collagen organization (CO) in human normal (n= 6),
degraded (n= 6) and repair (n= 22) cartilages, using polarized light (PLM) and scanning …

OBJECTIVE: The objective of this study was to elucidate the role of the superficial region of
articular cartilage in determining the dynamic properties of the tissue. It is hypothesised that …

When repairing cartilage defects a major challenge is achieving high-quality integration
between the repair tissue and adjacent native cartilage. Matrix-rich cartilage is not easily …

Fibrillar type I collagen, the predominant organic component in bone, is stabilized by lysyl
oxidase (LOX)-initiated covalent intermolecular cross-linking, an important determinant of …