International consensus statement on allergy and rhinology: Allergic rhinitis–2023
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …
Atopic dermatitis: an expanding therapeutic pipeline for a complex disease
T Bieber - Nature reviews Drug discovery, 2022 - nature.com
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex
pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains …
pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains …
Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?
CA Akdis - Nature Reviews Immunology, 2021 - nature.com
There has been a steep increase in allergic and autoimmune diseases, reaching epidemic
proportions and now affecting more than one billion people worldwide. These diseases are …
proportions and now affecting more than one billion people worldwide. These diseases are …
Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
Nomenclature of allergic diseases and hypersensitivity reactions: Adapted to modern needs: An EAACI position paper
The exponential growth of precision diagnostic tools, including omic technologies, molecular
diagnostics, sophisticated genetic and epigenetic editing, imaging and nano‐technologies …
diagnostics, sophisticated genetic and epigenetic editing, imaging and nano‐technologies …
[HTML][HTML] Immunoglobulin signature predicts risk of post-acute COVID-19 syndrome
Following acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) a significant proportion of individuals develop prolonged symptoms, a serious condition …
2) a significant proportion of individuals develop prolonged symptoms, a serious condition …
[HTML][HTML] Effect of dupilumab on blood eosinophil counts in patients with asthma, chronic rhinosinusitis with nasal polyps, atopic dermatitis, or eosinophilic esophagitis
Background Transient increases in blood eosinophil counts have been observed in
dupilumab clinical trials. Objective To assess eosinophil counts and eosinophilia-related …
dupilumab clinical trials. Objective To assess eosinophil counts and eosinophilia-related …
EAACI Biologicals Guidelines—Recommendations for severe asthma
Severe asthma imposes a significant burden on patients, families and healthcare systems.
Management is difficult, due to disease heterogeneity, co‐morbidities, complexity in care …
Management is difficult, due to disease heterogeneity, co‐morbidities, complexity in care …
Advances and highlights in asthma in 2021
I Agache, I Eguiluz‐Gracia, C Cojanu, A Laculiceanu… - Allergy, 2021 - Wiley Online Library
Last year brought a significant advance in asthma management, unyielding to the pressure
of the pandemics. Novel key findings in asthma pathogenesis focus on the resident cell …
of the pandemics. Novel key findings in asthma pathogenesis focus on the resident cell …
Cellular and molecular mechanisms of allergic asthma
Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
worldwide. It is the most common chronic disease in children, affecting at least 30 million …