Recent update on the heterogeneity of the Alzheimer's disease spectrum
KA Jellinger - Journal of Neural Transmission, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia worldwide, is a mixed
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …
The heterogeneity of late-life depression and its pathobiology: a brain network dysfunction disorder
KA Jellinger - Journal of Neural Transmission, 2023 - Springer
Depression is frequent in older individuals and is often associated with cognitive impairment
and increasing risk of subsequent dementia. Late-life depression (LLD) has a negative …
and increasing risk of subsequent dementia. Late-life depression (LLD) has a negative …
Understanding the lived experiences of family caregivers of individuals with dementia in Soweto, a South African Township
A Mahomed, C Pretorius - Dementia, 2022 - journals.sagepub.com
This study was undertaken to understand South African family caregivers' lived experiences
of individuals living with dementia in a predominantly Black African township. A …
of individuals living with dementia in a predominantly Black African township. A …
Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer's disease
R Keszycki, G Rodriguez, JT Dunn, A Locci… - Neurobiology of …, 2023 - Elsevier
Most patients with Alzheimer's disease (AD) develop neuropsychiatric symptoms (NPS)
alongside cognitive decline, and apathy is one of the most common symptoms. Few …
alongside cognitive decline, and apathy is one of the most common symptoms. Few …
Informant-rated change in personality traits, psychological distress, well-being, and social connection with dementia
AR Sutin, M Luchetti, Y Stephan… - Archives of Gerontology …, 2023 - Elsevier
Objectives Studies of retrospective personality change with dementia consistently find
caregivers report large changes in personality (eg, increases in neuroticism) of their care …
caregivers report large changes in personality (eg, increases in neuroticism) of their care …
The Impact of Rhythmic Physical Activity on Mental Health and Quality of Life in Older Adults with and without Cognitive Impairment: A Systematic Review and Meta …
M Sanchez-Alcala, A Aibar-Almazan… - Journal of Clinical …, 2023 - mdpi.com
(1) Background: Nowadays, it is essential to implement new non-pharmacological
strategies, such as rhythmic physical activity, to improve mental health and quality of life in …
strategies, such as rhythmic physical activity, to improve mental health and quality of life in …
Specific agitation behaviours in dementia differentially contribute to aspects of caregiver burden
KS Patrick, J Gunstad, JT Martin, KR Chapman… - …, 2022 - Wiley Online Library
Background Agitation is a common symptom in dementia and linked to caregiver burden, but
both agitation and burden are multidimensional constructs. The current study sought to …
both agitation and burden are multidimensional constructs. The current study sought to …
Dyadic Ambivalence in Couples Managing Early-Stage Alzheimer's Disease: Linking Behavioral and Psychological Symptoms of Dementia to Life Satisfaction
Objectives Caring for a spouse with Alzheimer's disease (AD) can elicit considerable
distress but there are also positive moments. A growing body of work has examined …
distress but there are also positive moments. A growing body of work has examined …
Neuropsychiatric symptoms as a prodromal factor in Alzheimer's type neurodegenerative disease: A scoping review
DA Ferreira, LBC Macedo, MP Foss - The Clinical …, 2024 - Taylor & Francis
Objective: Identifying neuropsychiatric symptoms (NPS) can aid in the early detection of
Alzheimer's disease (AD); however, there is still a need for a greater consensus. This review …
Alzheimer's disease (AD); however, there is still a need for a greater consensus. This review …
The reporting of neuropsychiatric symptoms in electronic health records of individuals with Alzheimer's disease: a natural language processing study
WS Eikelboom, EH Singleton, E van den Berg… - Alzheimer's Research & …, 2023 - Springer
Background Neuropsychiatric symptoms (NPS) are prevalent in the early clinical stages of
Alzheimer's disease (AD) according to proxy-based instruments. Little is known about which …
Alzheimer's disease (AD) according to proxy-based instruments. Little is known about which …