Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …

Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …

Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …

In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …

The environmental soot and carbon blacks (CBs) cause many diseases in humans, but their
underlying mechanisms of toxicity are still poorly understood. Both are formed after the …

Asthma is a T lymphocyte–controlled disease of the airway wall caused by inflammation,
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …

The mammalian inflammatory response is a rapid and complex physiological reaction to
noxious stimuli including microbial pathogens. Although inflammation plays a valuable role …

Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Asthma has been considered a T helper 2 (TH2) cell-associated inflammatory disease, and
TH2-type cytokines, such as interleukin-4 (IL-4), IL-5 and IL-13, are thought to drive the …

Abstract CD4+ T helper (TH) cells regulate appropriate cellular and humoral immune
responses to a wide range of pathogens and are central to the success of vaccines …