The heart balances uptake, metabolism and oxidation of fatty acids (FAs) to maintain ATP
production, membrane biosynthesis and lipid signaling. Under conditions where FA uptake …

Heart failure (HF) involves changes in cardiac structure, myocardial composition, myocyte
deformation, and multiple biochemical and molecular alterations that impact heart function …

Heart failure (HF) afflicts about 5 million people and causes 300 000 deaths a year in the
United States alone. An integral part of the pathogenesis of HF is cardiac remodelling, and …

Heart failure (HF) is a physiological state in which cardiac output is insufficient to meet the
needs of the body. It is a clinical syndrome characterized by impaired ability of the left …

Protein kinase C (PKC) is comprised of a family of signal-regulated enzymes that play
pleiotropic roles in the control of many physiological and pathological responses. PKC …

Protein kinase C (PKC) is a family of phospholipid‐dependent serine/threonine kinases,
which can be further classified into three PKC isozymes subfamilies: conventional or classic …

Protein kinase C (PKC) is a family of kinases that are implicated in a plethora of diseases,
including cancer and cardiovascular disease. PKC isoforms can have different, and …

Protein kinase C (PKC) comprises a family of lipid-sensitive enzymes that have been
involved in a broad range of cellular functions. PKC-α is a member of classical PKC with …

Background Apelin, the endogenous ligand for the G protein-coupled apelin receptor, is an
important regulator of the cardiovascular homoeostasis. We previously demonstrated that …

Protein kinase C (PKC) is a family of Ser/Thr kinases that regulate a multitude of cellular
processes through participation in the phosphoinositide signaling pathway. Significant …