Breast cancer is the second most frequent cancer in the world. It is a heterogeneous disease
and the leading cause of cancer mortality in women. Advances in molecular technologies …

Surgery remains the cornerstone of achieving breast cancer control, but understanding the
biological and molecular processes that drive breast cancer development, coupled with the …

Abstract Purpose of Review To explore how genomic testing has changed local therapy
decision-making, specifically surgical timing and opportunities for de-escalation of radiation …

Introduction Traditionally, sentinel lymph node biopsy (SLNB) was performed to inform
adjuvant chemotherapy prescription and prognosis in breast cancer. Following RxPONDER …

Abstract Purpose Caveolin-1 (CAV1) has been implicated in breast cancer oncogenesis and
metastasis and may be a potential prognosticator, especially for non-distant events. CAV1 …

Background Recent studies have shown a lower likelihood of locoregional recurrences in
patients with a low 21-gene recurrence score (RS). In this single-institution study, we …

乳腺癌是女性发病率最高的恶性肿瘤. 随着基因组学技术和医学前沿技术的发展,
乳腺癌的全身治疗逐渐进入个体化医疗时代. 但是乳腺癌的辅助放疗决策仍然主要依赖于临床 …

Breast cancer is the most common malignant tumor in women. With the development of
genomics technology and medical frontier technology, the systemic treatment of breast …

Background In those with one to three positive lymph nodes (N1) breast cancer (BC), the 21-
gene recurrence score (RS) classification can be referred for decision-making on adjuvant …