The role of allergen‐specific IgE, IgG and IgA in allergic disease

MH Shamji, R Valenta, T Jardetzky, V Verhasselt… - Allergy, 2021 - Wiley Online Library
Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease
affecting more than 30% of the population. Exposure to even minute quantities of allergens …

Allergen immunotherapy in children user's guide

M Alvaro‐Lozano, CA Akdis, M Akdis… - Pediatric allergy and …, 2020 - Wiley Online Library
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

EAACI molecular allergology user's guide 2.0

S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

[HTML][HTML] Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers

MH Shamji, SR Durham - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

Mechanisms of allergen immunotherapy in allergic rhinitis

G Drazdauskaitė, JA Layhadi, MH Shamji - Current allergy and asthma …, 2021 - Springer
Abstract Purpose of Review Allergic rhinitis (AR) is a chronic inflammatory immunoglobulin
(Ig) E-mediated disease of the nasal mucosa that can be triggered by the inhalation of …

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper

MH Shamji, JH Kappen, M Akdis, E Jensen‐Jarolim… - Allergy, 2017 - Wiley Online Library
Background Allergen immunotherapy (AIT) is an effective treatment for allergic
rhinoconjunctivitis (AR) with or without asthma. It is important to note that due to the complex …

[HTML][HTML] Sublingual immunotherapy: World Allergy Organization position paper 2013 update

GW Canonica, L Cox, R Pawankar… - World Allergy …, 2014 - Elsevier
We have prepared this document,“Sublingual Immunotherapy: World Allergy Organization
Position Paper 2013 Update”, according to the evidence-based criteria, revising and …

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement

JM Orengo, AR Radin, V Kamat, A Badithe… - Nature …, 2018 - nature.com
Acute allergic symptoms are caused by allergen-induced crosslinking of allergen-specific
immunoglobulin E (IgE) bound to Fc-epsilon receptors on effector cells. Desensitization with …

SQ-standardized sublingual grass immunotherapy: confirmation of disease modification 2 years after 3 years of treatment in a randomized trial

SR Durham, W Emminger, A Kapp… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: The main aim of specific immunotherapy is sustained effect due to changes
in the immune system that can be demonstrated only in long-term trials. OBJECTIVE: To …

Sub-Lingual Immunotherapy: World Allergy Organization Position Paper 2009

GW Canonica, J Bousquet, T Casale… - World Allergy …, 2009 - Springer
Sublingual immunotherapy (SLIT) has gained wide accep-tance in many European
countries and has raised the level of interest in immunotherapy among practicing allergists …