Molecular mechanisms of environmental exposures and human disease

H Wu, CM Eckhardt, AA Baccarelli - Nature reviews genetics, 2023 - nature.com
A substantial proportion of disease risk for common complex disorders is attributable to
environmental exposures and pollutants. An appreciation of how environmental pollutants …

Inflammatory effects of particulate matter air pollution

RD Arias-Pérez, NA Taborda, DM Gómez… - … Science and Pollution …, 2020 - Springer
Air pollution is an important cause of non-communicable diseases globally with particulate
matter (PM) as one of the main air pollutants. PM is composed of microscopic particles that …

[HTML][HTML] Air pollution and DNA methylation: effects of exposure in humans

CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …

Cardiovascular effects of particulate air pollution

A Bhatnagar - Annual Review of Medicine, 2022 - annualreviews.org
Inhalation of fine particulate matter (PM2. 5), produced by the combustion of fossil fuels, is
an important risk factor for cardiovascular disease. Exposure to PM2. 5 has been linked to …

Clinical effects of air pollution on the central nervous system; a review

RM Babadjouni, DM Hodis, R Radwanski… - Journal of Clinical …, 2017 - Elsevier
The purpose of this review is to describe recent clinical and epidemiological studies
examining the adverse effects of urban air pollution on the central nervous system (CNS). Air …

The relationship between particulate matter and lung function of children: A systematic review and meta-analysis

W Zhang, R Ma, Y Wang, N Jiang, Y Zhang, T Li - Environmental Pollution, 2022 - Elsevier
There have been many studies on the relationship between fine particulate matter (PM 2.5)
and lung function. However, the impact of short-term or long-term PM 2.5 exposures on lung …

Environmental exposures and cardiovascular disease: a challenge for health and development in low-and middle-income countries

MSB Pena, A Rollins - Cardiology clinics, 2017 - cardiology.theclinics.com
In the wake of large-scale economic development in low-and middle-income countries
(LMIC), environmental pollution has been a challenge that has spurred tension within …

[HTML][HTML] Long-term exposure to ambient air pollution and metabolic syndrome in children and adolescents: a national cross-sectional study in China

JS Zhang, ZH Gui, ZY Zou, BY Yang, J Ma, J Jing… - Environment …, 2021 - Elsevier
Background The prevalence of metabolic syndrome (MetS) rapidly increased over the past
decades. However, little evidence exists about the effects of long-term exposure to ambient …

[HTML][HTML] Gut microbiota partially mediates the effects of fine particulate matter on type 2 diabetes: evidence from a population-based epidemiological study

T Liu, X Chen, Y Xu, W Wu, W Tang, Z Chen, G Ji… - Environment …, 2019 - Elsevier
Background Experimental studies have indicated that alterations in the gut microbiota might
play a role in the pathway of diabetes induction resulting from particulate matter pollution …

[HTML][HTML] DNA methylation: a potential mediator between air pollution and metabolic syndrome

P Poursafa, Z Kamali, E Fraszczyk, HM Boezen… - Clinical …, 2022 - Springer
Given the global increase in air pollution and its crucial role in human health, as well as the
steep rise in prevalence of metabolic syndrome (MetS), a better understanding of the …