Emerging drugs for the treatment of herpetic keratitis

D Kapoor, P Sharma, D Shukla - Expert Opinion on Emerging …, 2024 - Taylor & Francis
Introduction Herpes simplex keratitis stands as a prominent factor contributing to infectious
blindness among developed nations. On a global scale, over 60% of the population tests …

[HTML][HTML] Herpes simplex keratitis: A brief clinical overview

M Musa, E Enaholo, G Aluyi-Osa… - World Journal of …, 2024 - ncbi.nlm.nih.gov
The aim of our minireview is to provide a brief overview of the diagnosis, clinical aspects,
treatment options, management, and current literature available regarding herpes simplex …

Metabolomics Profiles Reveal New Insights of Herpes Simplex Virus Type 1 Infection

P Huang, X Wang, M Lei, Y Ma, H Chen, J Sun… - International Journal of …, 2023 - mdpi.com
Herpes simplex virus type 1 (HSV-1) is a ubiquitous human pathogen that can cause
significant morbidity, primarily facial cold sores and herpes simplex encephalitis. Previous …

Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis

H Ma, T Chen, C Li, H Xu, Q Feng, Y Su, J Cai, Q Zhu… - The Ocular Surface, 2024 - Elsevier
Purpose Herpes simplex keratitis (HSK), caused by type 1 herpes simplex virus (HSV)
reactivation, is a severe infectious disease that leads to vision loss. HSV can trigger …

Oral administration of S-nitroso-l-glutathione (GSNO) provides anti-inflammatory and cytoprotective effects during ocular bacterial infections

S Das, Z Ahmad, S Singh, S Singh, RE Wright III… - Cellular and Molecular …, 2023 - Springer
Bacterial endophthalmitis is a severe complication of eye surgeries that can lead to vision
loss. Current treatment involves intravitreal antibiotic injections that control bacterial growth …

[HTML][HTML] HerpDock: A GUI-based gateway to HSV-1 molecular docking insights

SK Singh, D Kapoor, D Shukla - Computational and Structural …, 2024 - Elsevier
Abstract Herpes Simplex Virus 1 (HSV-1) is a member of the alpha-Herpesviridae family,
with over 60% of the global population being seropositive. HSV-1 can cause a range of …

Herpes simplex type 1 UL43 multiple membrane-spanning protein increases energy metabolism in host cells through interacting with ARL2

J Deng, Z Zhong, C Geng, Z Dai, W Zheng, Z Li, Z Yan… - Cells, 2022 - mdpi.com
Non-essential proteins for viral replication affect host cell metabolism, while the function of
the UL43 protein of herpes simplex virus 1 (HSV-1) is not clear. Herein, we performed a …

Tunneling Nanotubes: The Cables for Viral Spread and Beyond

D Kapoor, P Sharma, A Saini, E Azhar, J Elste… - … and Communication in …, 2024 - Springer
Multicellular organisms require cell-to-cell communication to maintain homeostasis and
thrive. For cells to communicate, a network of filamentous, actin-rich tunneling nanotubes …