Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of
cardiometabolic diseases, including coronary artery disease, diabetes mellitus …

In addition to their role in glucose and lipid metabolism, adipocytes respond differentially to
physiological cues or metabolic stress by releasing endocrine factors that regulate diverse …

The global prevalence of metabolic diseases such as type 2 diabetes mellitus,
steatohepatitis, myocardial infarction, and stroke has increased dramatically over the past …

There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …

Defects in insulin signalling are among the most common and earliest defects that
predispose an individual to the development of type 2 diabetes,,. MicroRNAs have been …

Vitamin A is required for important physiological processes, including embryogenesis,
vision, cell proliferation and differentiation, immune regulation, and glucose and lipid …

Nearly all stress stimuli (eg, inflammatory cytokines, glucocorticoids, chemotherapeutics,
etc.) induce sphingolipid synthesis, leading to the accumulation of ceramides and ceramide …

The retinoids are a class of compounds that are structurally related to vitamin A. Retinoic
acid, which is the active metabolite of retinol, regulates a wide range of biological processes …

Non-alcoholic fatty liver disease is one of the most common chronic liver diseases, ranging
from simple steatosis to steatohepatitis, fibrosis, and cirrhosis. Its prevalence is rapidly …