Management of acquired haemophilia A
PW Collins - Journal of Thrombosis and Haemostasis, 2011 - Wiley Online Library
Acquired haemophilia A is an auto‐immune disease caused by an inhibitory antibody to
factor VIII. The pattern of bleeding varies but patients remain at risk of life threatening …
factor VIII. The pattern of bleeding varies but patients remain at risk of life threatening …
Acquired hemophilia a: diagnosis, aetiology, clinical spectrum and treatment options
S Shetty, M Bhave, K Ghosh - Autoimmunity reviews, 2011 - Elsevier
Acquired hemophilia A (AHA) is a rare disorder with an incidence of approximately 1 per
million/year with a high mortality rate of more than 20%. The disease occurs due to …
million/year with a high mortality rate of more than 20%. The disease occurs due to …
Advances in the understanding of acquired haemophilia A: implications for clinical practice
PW Collins, CL Percy - British journal of haematology, 2010 - Wiley Online Library
Acquired haemophilia A is an auto‐immune disease caused by an inhibitory antibody to
factor VIII. Patients with an acquired factor VIII inhibitor are at risk of life‐and limb …
factor VIII. Patients with an acquired factor VIII inhibitor are at risk of life‐and limb …
Hemophilia in Iran
A Dorgalaleh, G Dadashizadeh, T Bamedi - Hematology, 2016 - Taylor & Francis
Background: Hemophilia A (HA) and B (HB) are common bleeding disorders, Iran having the
ninth largest such population in the world. A considerable number of studies have been …
ninth largest such population in the world. A considerable number of studies have been …
Recombinant activated factor VII: mechanisms of action and current indications
M Franchini, G Lippi - Seminars in thrombosis and hemostasis, 2010 - thieme-connect.com
Recombinant activated factor VII (rFVIIa) was initially developed to overcome the limitations
of existing treatments for patients with congenital hemophilia and inhibitors. Clinical success …
of existing treatments for patients with congenital hemophilia and inhibitors. Clinical success …
Ten‐year experience of recombinant activated factor VII use in surgical patients with congenital haemophilia with inhibitors or acquired haemophilia in Japan
H Takedani, M Shima, Y Horikoshi, T Koyama… - …, 2015 - Wiley Online Library
Patients with congenital haemophilia with inhibitors or acquired haemophilia are at risk of
bleeding complications during surgery. In these patients, replacement therapy for the …
bleeding complications during surgery. In these patients, replacement therapy for the …
Effect of BAX499 aptamer on tissue factor pathway inhibitor function and thrombin generation in models of hemophilia
INTRODUCTION: In hemophilia, thrombin generation is significantly suppressed due to
decreased factor (F) X activation. Clinical studies and experiments with transgenic mice …
decreased factor (F) X activation. Clinical studies and experiments with transgenic mice …
Hemostatic assessment, treatment strategies, and hematology consultation in massive postpartum hemorrhage: results of a quantitative survey of obstetrician …
AH James, DL Cooper, MJ Paidas - International journal of …, 2015 - Taylor & Francis
Objective To assess potential diagnostic and practice barriers to successful management of
massive postpartum hemorrhage (PPH), emphasizing recognition and management of …
massive postpartum hemorrhage (PPH), emphasizing recognition and management of …
First-line immunosuppressive therapies for acquired hemophilia A: A 25-year cohort experience and network meta-analysis
T Rungjirajittranon, B Suwanawiboon, Y Nakkinkun… - Thrombosis …, 2024 - Elsevier
Acquired hemophilia A (AHA) presents a significant bleeding risk. Management involves
bleeding control and immunosuppressive therapy (IST) to eliminate inhibitors. This study …
bleeding control and immunosuppressive therapy (IST) to eliminate inhibitors. This study …
Pregnancy-related acquired hemophilia A initially manifesting as pleural hemorrhage: a case report
L Qian, H Ge, P Hu, N Zhu, J Chen, J Shen, Y Zhang - Medicine, 2019 - journals.lww.com
Interventions: The treatment requires a 2-pronged approach: treatment of the bleeding and
elimination of the inhibitor. Outcomes: After hemostatic agents were used and inhibitors …
elimination of the inhibitor. Outcomes: After hemostatic agents were used and inhibitors …