Free radicals or reactive oxygen species (ROS) are generated by oxygen metabolism which
is balanced by the rate of oxidant formation and the rate of oxidant elimination. Oxidative …

The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

Significance: Reactive oxygen species (ROS) play a critical role in vascular disease. While
there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate …

Renin angiotensin system (RAS) is an endocrine system widely known for its physiological
roles in electrolyte homeostasis, body fluid volume regulation and cardiovascular control in …

Loneliness and social isolation are common sources of chronic stress in modern society.
Epidemiological studies have demonstrated that loneliness and social isolation increase …

Oxidative stress has been implicated in the pathogenesis of neurologic and psychiatric
diseases. The brain is particularly vulnerable to oxidative damage due to high oxygen …

A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …

Over the last decade many studies have demonstrated the importance of reactive oxygen
species (ROS) production by NADPH oxidases in angiotensin II (Ang II) signaling, as well as …

Nitroxides can undergo one-or two-electron reduction reactions to hydroxylamines or
oxammonium cations, respectively, which themselves are interconvertible, thereby providing …

The NADPH oxidase is a multi-subunit enzyme that catalyzes the reduction of molecular
oxygen to form superoxide (O2•−). While classically linked to the respiratory burst in …