Trends in insulin resistance: insights into mechanisms and therapeutic strategy
M Li, X Chi, Y Wang, S Setrerrahmane… - Signal transduction and …, 2022 - nature.com
The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - … and Targeted Therapy, 2023 - nature.com
Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
Epigenetic regulation of energy metabolism in obesity
W Gao, JL Liu, X Lu, Q Yang - Journal of molecular cell biology, 2021 - academic.oup.com
Obesity has reached epidemic proportions globally. Although modern adoption of a
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …
Circular RNAs in physiology and non-immunological diseases
Circular RNAs (circRNAs) are covalently closed single-stranded RNAs. Four subclasses of
circRNAs have been identified in animal cells, and they have unique features in their …
circRNAs have been identified in animal cells, and they have unique features in their …
Circular RNA in disease: basic properties and biomedical relevance
Circular RNAs (circRNAs) represent a class of covalently closed RNA molecules with great
diversity in molecular features, functions, and regulatory mechanisms. Emerging advances …
diversity in molecular features, functions, and regulatory mechanisms. Emerging advances …
The functions and clinical significance of circRNAs in hematological malignancies
X Zhou, L Zhan, K Huang, X Wang - Journal of hematology & oncology, 2020 - Springer
With covalently closed circular structures, circular RNAs (circRNAs) were once
misinterpreted as by-products of mRNA splicing. Being abundant, stable, highly conserved …
misinterpreted as by-products of mRNA splicing. Being abundant, stable, highly conserved …
Circular RNA profiling identifies novel circPPARA that promotes intramuscular fat deposition in pigs
B Li, Y He, W Wu, X Tan, Z Wang… - Journal of Agricultural …, 2022 - ACS Publications
Intramuscular fat (IMF) content plays an important role in pork quality. Circular RNAs
(circRNAs) implicate various biological processes; however, the regulatory mechanisms and …
(circRNAs) implicate various biological processes; however, the regulatory mechanisms and …
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop
Abstract Background Circular RNAs (circRNAs) represent a novel class of non‐coding RNAs
formed by a covalently closed loop and play crucial roles in many biological processes …
formed by a covalently closed loop and play crucial roles in many biological processes …
[HTML][HTML] Advances in multi-omics study of biomarkers of glycolipid metabolism disorder
X Fang, R Miao, J Wei, H Wu, J Tian - Computational and Structural …, 2022 - Elsevier
Glycolipid metabolism disorder are major threats to human health and life. Genetic,
environmental, psychological, cellular, and molecular factors contribute to their …
environmental, psychological, cellular, and molecular factors contribute to their …
Novel insights into the interaction between N6-methyladenosine modification and circular RNA
T Xu, B He, H Sun, M Xiong, J Nie, S Wang… - … Therapy-Nucleic Acids, 2022 - cell.com
As the most prevalent type of RNA modification in eukaryotes, N6-methyladenosine (m 6 A)
can modulate RNA fates such as processing, splicing, maturation, export, stability …
can modulate RNA fates such as processing, splicing, maturation, export, stability …