Bottom-up neuroscience, which consists of building and studying controlled networks of
neurons in vitro, is a promising method to investigate information processing at the neuronal …

Regulators of chromatin dynamics and transcription are increasingly implicated in the
aetiology of neurodevelopmental disorders. Haploinsufficiency of EHMT1, encoding a …

Kleefstra syndrome is a disorder caused by a mutation in the EHMT1 gene characterized in
humans by general developmental delay, mild to severe intellectual disability and autism …

Loss of function (LoF) mutations affecting the histone methyl transferase SETD1A are
implicated in the aetiology of a range of neurodevelopmental disorders including …

Monoamine oxidase A (MAOA) is an enzyme that catalyzes the degradation of dopamine,
noradrenaline, and serotonin. Regulation of monoamine neurotransmitter abundance …

Genetic evidence indicates disrupted epigenetic regulation as a major risk factor for
psychiatric disorders, but the molecular mechanisms that drive this association are …

Regulators of chromatin dynamics and transcription are increasingly implicated in the
aetiology of neurodevelopmental disorders (NDDs). Haploinsufficiency of EHMT1, encoding …