[HTML][HTML] Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases

A Ståhl, K Johansson, M Mossberg, R Kahn… - Pediatric …, 2019 - Springer
Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in
size, including exosomes, microvesicles, and apoptotic bodies. They are released under …

[HTML][HTML] Cell-free DNA as a biomarker in autoimmune rheumatic diseases

B Duvvuri, C Lood - Frontiers in immunology, 2019 - frontiersin.org
Endogenous DNA is primarily found intracellularly in nuclei and mitochondria. However,
extracellular, cell-free (cf) DNA, has been observed in several pathological conditions …

Emerging role of extracellular vesicles in inflammatory diseases

EI Buzas, B György, G Nagy, A Falus… - Nature Reviews …, 2014 - nature.com
The discovery that submicron-sized extracellular vesicles (EVs) are generated by both
prokaryotic and eukaryotic cells might have a profound effect on experimental and clinical …

[HTML][HTML] Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

B György, TG Szabó, M Pásztói, Z Pál, P Misják… - Cellular and molecular …, 2011 - Springer
Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes,
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells

DB Kell, E Pretorius - Metallomics, 2014 - academic.oup.com
Abstract" Serum ferritin" presents a paradox, as the iron storage protein ferritin is not
synthesised in serum yet is to be found there. Serum ferritin is also a well known …

Platelet microvesicles in health and disease

I Melki, N Tessandier, A Zufferey, E Boilard - platelets, 2017 - Taylor & Francis
Interest in cell-derived extracellular vesicles and their physiological and pathological
implications is constantly growing. Microvesicles, also known as microparticles, are small …

The role of neutrophils in thrombosis

S Kapoor, A Opneja, L Nayak - Thrombosis research, 2018 - Elsevier
Despite significant evidence implicating an important role for neutrophils in thrombosis, their
impact on the thrombotic process has remained a matter of controversy. Until 2010, platelets …

Microparticles: biomarkers and beyond

D Burger, S Schock, CS Thompson… - Clinical …, 2013 - portlandpress.com
Membrane microparticles are submicron fragments of membrane shed into extracellular
space from cells under conditions of stress/injury. They may be distinguished from other …

[HTML][HTML] Extracellular vesicles as potential biomarkers and therapeutic approaches in autoimmune diseases

K Xu, Q Liu, K Wu, L Liu, M Zhao, H Yang… - Journal of Translational …, 2020 - Springer
Extracellular vesicles are heterogeneous populations of naturally occurring secreted small
vesicles. EVs function as signaling platforms to facilitate intracellular communication, which …

The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle‐associated immune complexes

N Cloutier, S Tan, LH Boudreau, C Cramb… - EMBO molecular …, 2013 - embopress.org
Immunoglobulins, antigens and complement can assemble to form immune complexes (IC).
ICs can be detrimental as they propagate inflammation in autoimmune diseases. Like ICs …