A novel palladium (II) antitumor agent: Synthesis, characterization, DFT perspective, CT-DNA and BSA interaction studies via in-vitro and in-silico approaches

M Feizi-Dehnayebi, E Dehghanian… - … Acta Part A: Molecular …, 2021 - Elsevier
Since numerous people annually pass away due to cancer, research in this field is essential.
Thus a newly made and water like palladium (II) complex of formula [Pd (phen)(acac)] NO 3 …

A new zinc (II) complex of 2-benzoimidazoledisulfide ligand: synthesis, X-ray crystallographic structure, investigation of CT-DNA and BSA interaction by spectroscopic …

F Mohammadlou, H Mansouri-Torshizi… - … of Photochemistry and …, 2023 - Elsevier
This study reports a new zinc (II) complex based on 2-mercaptobenzimidazole ligand. It was
synthesized and characterized by UV–visible and Fourier transform infrared spectroscopy …

Effect of geometric isomerism on the anticancer property of new platinum complexes with glycine derivatives as asymmetric N, O donate ligands against human cancer

D Kadivar, ME Moghadam, B Notash - Spectrochimica Acta Part A …, 2024 - Elsevier
In this project, to fallow the anticancer ability of new Pt drugs, several new Pt complexes
were synthesized with the asymmetric bidentate glycine derivatives, as named propyl-and …

Spectroscopy, docking and molecular dynamics studies on the interaction between cis and trans palladium-alanine complexes with calf-thymus DNA and antitumor …

A Izadyar, H Mansouri-Torshizi… - Journal of …, 2023 - Taylor & Francis
The present article investigates whether the cis and trans isomers of the same compound
affect their antitumor and DNA-binding properties. Thus, we have synthesized cis-[Pd (L-Ala) …

Investigation of the physico-chemical interaction of ct-DNA with Anticancer Glycine Derivative of Pt-complex by applying docking and MD simulation methods and multi …

KT Hafshejani, N Sohrabi, ME Moghadam… - Journal of Molecular …, 2022 - Elsevier
The interaction of tertpentyl glycine derivative of platinum complex with ct-DNA was studied
by applying diverse spectroscopic methods (UV–vis and fluorescence quenching method …

Synthetic approach toward spiro quinoxaline-β-lactam based heterocyclic compounds: Spectral characterization, SAR, pharmacokinetic and biomolecular interaction …

RA Dabhi, MP Dhaduk, VD Bhatt… - Journal of Biomolecular …, 2023 - Taylor & Francis
Abstract Series of spiro quinoxaline-β-lactam based heterocyclic compounds (QL 1–QL 21)
were synthesized and characterized by spectroscopic techniques like 1H-NMR, LC-MS, FT …

Multispectroscopic analysis, atomic force microscopy, molecular docking and molecular dynamic simulation studies of the interaction between [SnMe2Cl2(Me2phen …

N Shahabadi, M Mahdavi… - Journal of Biomolecular …, 2021 - Taylor & Francis
In this study, the spectroscopic methods (UV–vis, fluorimetric), Atomic force microscopy, and
computational studies (molecular docking and molecular dynamic simulation) were used to …

New lanthanum (III) complexes containing azaphosphor β-diketon and diimine ligands: Synthesis, crystallography, morphology properties, DNA binding, DNA …

M Pass, N Dorosti, H Krautscheid - International Journal of Biological …, 2024 - Elsevier
Two octa-coordinated lanthanum (III) complexes of deprotonated azaphosphor β-diketon
and diimine ligands,[LnL 3 Q](L=[Cl 2 CHC (O) NP (O)(NC 6 H 12) 2], Q= Phen (C1) and …

[HTML][HTML] Structural, DNA/BSA binding interactions and cytotoxicity studies of carboxamide (pyridyl) pyrazine palladium (II) complexes

ST Mvelase, SO Benson, RO Omondi… - Journal of Molecular …, 2025 - Elsevier
Reactions of ligands [N 2, N 3-bis (pyridin-2-yl) pyrazine-2, 3-dicarboxamide](L1),[N 2, N 3-
bis (6-methylpyridin-2-yl) pyrazine-2, 3-dicarboxamide](L2),[N 2, N 3-bis (4-methylpyridin-2 …

Preparation, characterization, DNA/BSA interaction and computational binding analyses of a dinuclear, biopotency Pd+2 coordinated with 1,4-phenylenediamine and …

N Alisufi, H Mansouri-Torshizi - Journal of the Iranian Chemical Society, 2021 - Springer
A novel, dinuclear and dissolvable palladium (II) complex of [{Pd (en) Cl} 2 (μ-p-ph-da)](NO
3) 2, where en is ethylenediamine and p-ph-da is 1, 4-phenylenediamine, was synthesized …