[HTML][HTML] Systematic review and meta-analysis of esophageal cancer in Africa: epidemiology, risk factors, management and outcomes
AW Asombang, N Chishinga, A Nkhoma… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Esophageal cancer (EC) is associated with a poor prognosis, particularly so
in Africa where an alarmingly high mortality to incidence ratio prevails for this disease. AIM …
in Africa where an alarmingly high mortality to incidence ratio prevails for this disease. AIM …
The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma
K Ma, B Cao, M Guo - Clinical epigenetics, 2016 - Springer
Esophageal cancer is one of the most common malignancies in the world. Squamous cell
carcinoma accounts for approximately 90% of esophageal cancer cases. Genetic and …
carcinoma accounts for approximately 90% of esophageal cancer cases. Genetic and …
Identification of disulfidptosis related subtypes, characterization of tumor microenvironment infiltration, and development of DRG prognostic prediction model in RCC …
K Xu, Y Zhang, Z Yan, Y Wang, Y Li, Q Qiu… - Frontiers in …, 2023 - frontiersin.org
Disulfidptosis is a newly discovered mode of cell death induced by disulfide stress.
However, the prognostic value of disulfidptosis-related genes (DRGs) in renal cell …
However, the prognostic value of disulfidptosis-related genes (DRGs) in renal cell …
[HTML][HTML] The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer
D Gao, JG Herman, M Guo - Oncotarget, 2016 - ncbi.nlm.nih.gov
The stability and integrity of the human genome are maintained by the DNA damage repair
(DDR) system. Unrepaired DNA damage is a major source of potentially mutagenic lesions …
(DDR) system. Unrepaired DNA damage is a major source of potentially mutagenic lesions …
Smoking and DNA methylation: correlation of methylation with smoking behavior and association with diseases and fetus development following prenatal exposure
Among epigenetic mechanisms, DNA methylation has been widely studied with respect to
many environmental factors. Smoking is a common factor which affects both global and …
many environmental factors. Smoking is a common factor which affects both global and …
HIV infection and domestic smoke exposure, but not human papillomavirus, are risk factors for esophageal squamous cell carcinoma in Zambia: a case–control study
V Kayamba, AC Bateman, AW Asombang… - Cancer …, 2015 - Wiley Online Library
There is emerging evidence that esophageal cancer occurs in younger adults in sub‐
Saharan Africa than in Europe or North America. The burden of human immunodeficiency …
Saharan Africa than in Europe or North America. The burden of human immunodeficiency …
Identification of DNA methylation-driven genes in esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas
T Lu, D Chen, Y Wang, X Sun, S Li, S Miao, Y Wo… - Cancer cell …, 2019 - Springer
Background Aberrant DNA methylations are significantly associated with esophageal
squamous cell carcinoma (ESCC). In this study, we aimed to investigate the DNA …
squamous cell carcinoma (ESCC). In this study, we aimed to investigate the DNA …
Epigenomics-guided drug development: recent advances in solving the cancer treatment “jigsaw puzzle”
K Dzobo - Omics: a journal of integrative biology, 2019 - liebertpub.com
The human epigenome plays a key role in determining cellular identity and eventually
function. Drug discovery undertakings have focused mainly on the role of genomics in …
function. Drug discovery undertakings have focused mainly on the role of genomics in …
Cancer stem cell markers in relation to patient survival outcomes: lessons for integrative diagnostics and next-generation anticancer drug development
K Dzobo, C Ganz, NE Thomford… - Omics: a journal of …, 2021 - liebertpub.com
Solid tumors display a complex biology that requires a multipronged treatment strategy. Most
anticancer interventions, including chemotherapy, are currently unable to prevent treatment …
anticancer interventions, including chemotherapy, are currently unable to prevent treatment …
Expression and methylation of circulating microRNA-510 in essential hypertension
R Krishnan, P Mani, P Sivakumar, V Gopinath… - Hypertension …, 2017 - nature.com
Hypertension (HTN) is one of the most common emerging disease in developing countries. It
alters endothelial cell structure and function, resulting in several diseases, such as …
alters endothelial cell structure and function, resulting in several diseases, such as …