Retrotransposons have generated about 40% of the human genome. This review examines
the strategies the cell has evolved to coexist with these genomic “parasites”, focussing on …

Transposable elements (TEs) or “jumping genes” historically have been disparaged as a
class of “junk DNA” in mammalian genomes (1, 2). The advent of whole genome DNA …

Transposable Elements (TE) are mobile DNA elements that can replicate and insert
themselves into different locations within the host genome. Their propensity to self …

Despite often being classified as selfish or junk DNA, transposable elements (TEs) are a
group of abundant genetic sequences that have a significant impact on mammalian …

Transposable elements (TEs) are notable drivers of genetic innovation. Over evolutionary
time, TE insertions can supply new promoter, enhancer, and insulator elements to protein …

LINE-1 (L1) retrotransposons represent approximately one sixth of the human genome, but
only the human-specific L1HS-Ta subfamily acts as an endogenous mutagen in modern …

ABSTRACT Long interspersed element‐1 (LINE‐1 or L1) is a transposable element with the
ability to self‐mobilize throughout the human genome. The L1 elements found in the human …

When mammalian cells detect a viral infection, they initiate a type I interferon (IFNs)
response as part of their innate immune system. This antiviral mechanism is conserved in …

In plants, the accumulation of carotenoids can maintain the balance of the photosystem and
improve crop nutritional quality. Therefore, the molecular mechanisms underlying carotenoid …

Background: Transposable elements (TEs) are major components of eukaryotic genomes.
The extensive body of evidence suggests that although they were once considered …