MBOAT7 is a protein anchored to endomembranes by several transmembrane domains. It
has a catalytic dyad involved in remodelling of phosphatidylinositol with polyunsaturated …

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a complex multifactorial
disease and becoming the leading cause of liver-related morbidity and mortality. MASLD …

Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer.
Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those …

Recent advances in the genetics of metabolic dysfunction-associated steatotic liver disease
(MASLD) are gradually revealing the mechanisms underlying the heterogeneity of the …

Hepatic steatosis, the buildup of neutral lipids in lipid droplets (LDs), is commonly referred to
as metabolic dysfunction-associated steatotic liver disease (MASLD) when alcohol or viral …

Non-alcoholic fatty liver disease (NAFLD) is a common and prevalent disorder affecting 25
percent of the adults in the United States and 32 percent of adults globally. It is one of the …

I present a powerful and flexible backmapping tool named Multiscale Simulation Tool
(mstool) that converts a coarse-grained (CG) system into all-atom (AA) resolution and only …

The membrane-bound O-acyltransferase domain-containing 7 (MBOAT7) protein is an
acyltransferase catalyzing arachidonic acid incorporation into lysophosphatidylinositol …

Simple Summary This review discusses the enzymatic processes governing the initial
stages of the synthesis of glycerophospholipids (phosphatidylcholine …

Membrane-bound O-acyltransferases (MBOATs) are membrane-embedded enzymes that
catalyze acyl chain transfer to a diverse group of substrates, including lipids, small …