Parahydrogen‐Induced Polarization of Amino Acids
AN Pravdivtsev, G Buntkowsky… - Angewandte Chemie …, 2021 - Wiley Online Library
Nuclear magnetic resonance (NMR) has become a universal method for biochemical and
biomedical studies, including metabolomics, proteomics, and magnetic resonance imaging …
biomedical studies, including metabolomics, proteomics, and magnetic resonance imaging …
Catalyst-Free Aqueous Hyperpolarized [1-13C]Pyruvate Obtained by Re-Dissolution Signal Amplification by Reversible Exchange
Despite great successes in oncology, patient outcomes are often still discouraging, and
hence the diagnostic imaging paradigm is increasingly shifting toward functional imaging of …
hence the diagnostic imaging paradigm is increasingly shifting toward functional imaging of …
Hyperpolarized Carbon 13 MRI: Clinical Applications and Future Directions in Oncology
Hyperpolarized carbon 13 MRI (13C MRI) is a novel imaging approach that can
noninvasively probe tissue metabolism in both normal and pathologic tissues. The process …
noninvasively probe tissue metabolism in both normal and pathologic tissues. The process …
Quantification of Prostate Cancer Metabolism Using 3D Multiecho bSSFP and Hyperpolarized [1‐13C] Pyruvate: Metabolism Differs Between Tumors of the Same …
R Chowdhury, CA Mueller, L Smith… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Three‐dimensional (3D) multiecho balanced steady‐state free precession (ME‐
bSSFP) has previously been demonstrated in preclinical hyperpolarized (HP) 13C‐MRI in …
bSSFP) has previously been demonstrated in preclinical hyperpolarized (HP) 13C‐MRI in …
Spectrally selective bSSFP using off‐resonant RF excitations permits high spatiotemporal resolution 3D metabolic imaging of hyperpolarized [1‐13C] Pyruvate‐to‐[1 …
JG Skinner, GJ Topping, L Nagel, I Heid… - Magnetic …, 2023 - Wiley Online Library
Purpose To develop a high spatiotemporal resolution 3D dynamic pulse sequence for
preclinical imaging of hyperpolarized [1‐13C] pyruvate‐to‐[1‐13C] lactate metabolism at 7T …
preclinical imaging of hyperpolarized [1‐13C] pyruvate‐to‐[1‐13C] lactate metabolism at 7T …
Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions
Dissolution dynamic nuclear polarization (dDNP) increases the sensitivity of magnetic
resonance imaging by more than 10,000 times, enabling in vivo metabolic imaging to be …
resonance imaging by more than 10,000 times, enabling in vivo metabolic imaging to be …
Spatio-temporal reconstruction of substance dynamics using compressed sensing in multi-spectral magnetic resonance spectroscopic imaging
U Yamamoto, H Imai, K Sano, M Ohzeki… - Expert Systems with …, 2023 - Elsevier
The objective of our study is to observe dynamics of multiple substances in vivo with high
temporal resolution from multi-spectral magnetic resonance spectroscopic imaging (MRSI) …
temporal resolution from multi-spectral magnetic resonance spectroscopic imaging (MRSI) …
Considerations for hyperpolarized 13C MR at reduced field: Comparing 1.5T versus 3T
Purpose In contrast to conventional MR, signal‐to‐noise ratio (SNR) is not linearly
dependent on field strength in hyperpolarized MR, as polarization is generated outside the …
dependent on field strength in hyperpolarized MR, as polarization is generated outside the …
[HTML][HTML] High field para hydrogen induced polarization of succinate and phospholactate
S Berner, AB Schmidt, F Ellermann… - Physical Chemistry …, 2021 - pubs.rsc.org
The signal enhancement provided by the hyperpolarization of nuclear spins of metabolites is
a promising technique for diagnostic magnetic resonance imaging (MRI). To date, most 13C …
a promising technique for diagnostic magnetic resonance imaging (MRI). To date, most 13C …
A vendor‐neutral EPI sequence for hyperpolarized 13C MRI
T Blazey, A Shaw, C von Morze - Magnetic resonance in …, 2024 - Wiley Online Library
Purpose To develop a flexible, vendor‐neutral EPI sequence for hyperpolarized 13C
metabolic imaging. Methods An open‐source EPI sequence consisting of a metabolite …
metabolic imaging. Methods An open‐source EPI sequence consisting of a metabolite …