Infection is a dynamic biological process underpinned by a complex interplay between the
pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi …

Nucleotide oligomerization and binding domain (NOD)‐like receptors (NLR s) are a major
constituent of the cytosolic innate immune‐sensing machinery and participate in a wide …

Chronic HIV-1 infection is generally characterized by progressive CD4+ T cell depletion due
to direct and bystander death that is closely associated with persistent HIV-1 replication and …

Background Human immunodeficiency virus type 1 (HIV-1) infects and activates innate
immune cells in the brain resulting in inflammation and neuronal death with accompanying …

Highlights•Advances in ALR mediated inflammasome activation in response to viral
DNA.•Viral virulence factors that impair inflammasome activation.•Host regulation of …

Human immunodeficiency virus type 1 (HIV-1) infection is a chronic disease without a known
cure. The advent of effective antiretroviral therapy (ART) has enabled people with HIV …

Although combined antiretroviral therapy (cART) is effective in inhibiting human
immunodeficiency virus type 1 (HIV-1) replication, it does not eradicate the virus because …

Background Tuberculosis (TB) and AIDS are the leading causes of infectious diseases
death worldwide. Here, we investigated the relationship between from single nucleotide …

The innate immunity and inflammatory response plays an important role in AD
pathogenesis. Recently, a wealth of information linking the activation of NLRP3 …

Problem: Only a small proportion of HPV+ women develop virus‐associated lesions and
cervical cancer, suggesting that other factors are involved in HPV+ keratinocyte …