Copper is an essential trace element in biological systems, maintaining the activity of
enzymes and the function of transcription factors. However, at high concentrations, copper …

Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of
copper and copper triggered cell death in the pathogenesis of cancers have attracted …

Superoxide is a primary oxygen radical that is produced when an oxygen molecule receives
one electron. Superoxide dismutase (SOD) plays a primary role in the cellular defense …

Copper is an essential element in cells; it can act as either a recipient or a donor of
electrons, participating in various reactions. However, an excess of copper ions in cells is …

The human body cannot store zinc reserves, so a deficiency can arise relatively quickly, eg,
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …

Copper is an essential micronutrient for human body and plays a vital role in various
biological processes including cellular respiration and free radical detoxification. Generally …

Introduction he human body has an elaborate system for managing and regulating the
amount of key trace metals circulating in blood and stored in cells. Nutrient metals from our …

Charcot described amyotrophic lateral sclerosis (ALS) in 1874. Despite progress, this
creeping paralysis, known colloquially as Lou Gehrig's disease, is still not visibly affected by …

Copper (Cu) is a redox-active metal ion essential for most aerobic organisms. Cu serves as
a catalytic and structural cofactor for enzymes that function in energy generation, iron …

Amyotrophic lateral sclerosis is a late-onset progressive neurodegenerative disease
affecting motor neurons. The etiology of most ALS cases remains unknown, but 2% of …