Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

Plant NLRs with Integrated Domains: Unity Makes Strength | Plant Physiology | Oxford
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INTRODUCTION How novel protein architectures evolve remains poorly understood. The
rearrangement of domains with preexisting functions into new composite architectures …

Transposable elements (TEs) are major components of all vertebrate genomes that can
cause deleterious insertions and genomic instability. However, depending on the specific …

Transforming growth factor β (TGF-β) increases epithelial cancer cell migration and
metastasis by inducing epithelial-mesenchymal transition (EMT). TGF-β also inhibits cell …

Lineage plasticity is a prominent feature of pancreatic ductal adenocarcinoma (PDA) cells,
which can occur via deregulation of lineage-specifying transcription factors. Here, we show …

Complex eukaryotes contain millions of transposable elements (TEs), comprising large
fractions of their nuclear genomes. TEs consist of structural, regulatory, and coding …

During evolution, several types of sequences pass through genomes. Along with mutations
and internal genetic tinkering, they are a useful source of genetic variability for adaptation …

Powdery mildew, caused by Blumeria graminis f. sp. tritici (Bgt), reduces wheat yields and
grain quality, thus posing a significant threat to global food security. Wild relatives of wheat …

The Hermes DNA transposon is a member of the eukaryotic hAT superfamily, and its
transposase forms a ring-shaped tetramer of dimers. Our investigation, combining …