[HTML][HTML] The machinery of exosomes: biogenesis, release, and uptake

SV Krylova, D Feng - International Journal of Molecular Sciences, 2023 - mdpi.com
Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are
secreted by cells into their surroundings. By transporting proteins, lipids, mRNA, miRNA …

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

M Mathieu, L Martin-Jaular, G Lavieu, C Théry - Nature cell biology, 2019 - nature.com
The ability of exosomes to transfer cargo from donor to acceptor cells, thereby triggering
phenotypic changes in the latter, has generated substantial interest in the scientific …

[HTML][HTML] Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells

E Bonsergent, E Grisard, J Buchrieser… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs), including exosomes, are thought to mediate intercellular
communication through the transfer of cargoes from donor to acceptor cells. Occurrence of …

Native and bioengineered extracellular vesicles for cardiovascular therapeutics

RC de Abreu, H Fernandes… - Nature reviews …, 2020 - nature.com
Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …

[HTML][HTML] Exosomes and exosome-inspired vesicles for targeted drug delivery

SG Antimisiaris, S Mourtas, A Marazioti - Pharmaceutics, 2018 - mdpi.com
The similarities between exosomes and liposomes, together with the high organotropism of
several types of exosomes, have recently prompted the development of engineered …

[HTML][HTML] Characterizing extracellular vesicles and their diverse RNA contents

EM Veziroglu, GI Mias - Frontiers in Genetics, 2020 - frontiersin.org
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …

Exosomes: Therapy delivery tools and biomarkers of diseases

L Barile, G Vassalli - Pharmacology & therapeutics, 2017 - Elsevier
Virtually all cells in the organism secrete extracellular vesicles (EVs), a heterogeneous
population of lipid bilayer membrane-enclosed vesicles that transport and deliver payloads …

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

J Kowal, G Arras, M Colombo… - Proceedings of the …, 2016 - National Acad Sciences
Extracellular vesicles (EVs) have become the focus of rising interest because of their
numerous functions in physiology and pathology. Cells release heterogeneous vesicles of …

Exosome–liposome hybrid nanoparticles deliver CRISPR/Cas9 system in MSCs

Y Lin, J Wu, W Gu, Y Huang, Z Tong… - Advanced …, 2018 - Wiley Online Library
Targeted delivery of clustered regularly interspaced short palindromic repeats
(CRISPR)/CRISPR‐associated protein 9 (Cas9) system to the receptor cells is essential for …

Drug loading techniques for exosome-based drug delivery systems

XM Xi, SJ Xia, R Lu - Die Pharmazie-An International Journal …, 2021 - ingentaconnect.com
Exosomes are bilayer membrane-coated extracellular vesicles measuring between 40 and
100 nm in diameter. As a natural carrier, exosomes have the advantages of low …