The extracellular matrix (ECM) is an important component of the tumor microenvironment
(TME), having several important roles related to the hallmarks of cancer. In cancer, multiple …

Simple Summary Biliary tract cancers (BTCs), comprising cancers of the bile ducts
(cholangiocarcinoma) as well as gallbladder cancers, continue to be challenging to treat …

Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically
approved applications use this technology. Most approaches, however, predict categorical …

Simple Summary We sought to provide a detailed overview of the immune landscape of
colorectal cancer in the largest study to date in terms of patient numbers and analyzed …

Background Cancer immunity is based on the interaction of a multitude of cells in the spatial
context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated …

Neuroblastoma (NB) is an enigmatic and deadliest pediatric cancer to treat. The major
obstacles to the effective immunotherapy treatments in NB are defective immune cells and …

IMPORTANCE Platinum-based chemotherapy is the backbone of standard-of-care treatment
for patients with advanced-stage, high-grade serous carcinoma (HGSC), the most common …

Tumor tissue engineering holds great promise for replicating the physiological and
behavioral characteristics of tumors in vitro. Advances in this field have led to new …

Background Lung cancer remains the major cause of cancer‐related deaths worldwide.
Early stages of lung cancer are characterized by long asymptomatic periods that are …

Simple Summary Tumor cells struggle to survive following treatment. The struggle ends in
either of two ways. The drug combination used for the treatment blocks the proliferation of …