Multiple sclerosis (MS) is a common neurological disorder of putative autoimmune origin.
Clinical studies delineate abnormal expression of specific cytokines over the course of …

Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system. The complement system has an established role in the …

To identify genes and biologically relevant pathways associated with risk to develop multiple
sclerosis (MS), the Genome-Wide Association Studies noise reduction method (GWAS-NR) …

Spinal cord injury (SCI) leads to glial scar formation by astrocytes, which severely hinders
neural regeneration. Curcumin (cur) can inhibit glial scar formation, but the underlying …

Multiple sclerosis (MS) is a demyelinating disease characterized by chronic inflammation of
the central nervous system, in which many factors can act together to influence disease …

SIRT1 is a member of the histone deacetylase (HDAC) class III family of proteins and is an
NAD-dependent histone and protein deacetylase. SIRT1 can induce chromatin silencing …

Multiple sclerosis (MS) is a complex demyelinating disease of the central nervous system,
presenting with different clinical forms, including clinically isolated syndrome (CIS), which is …

The pathogenesis of atherosclerotic inflammation is a multi-step process defined by the
interweaving of excess modified lipid particles, monocyte-macrophages populations, and …

Response gene to complement 32 (RGC-32) is a cell cycle regulator involved in the
proliferation, differentiation and migration of cells and has also been implicated in …

We have previously shown that RGC-32 is involved in cell cycle regulation in vitro. To define
the in vivo role of RGC-32, we generated RGC-32 knockout mice. These mice developed …