Alzheimer's disease (AD) is the most common cause of dementia worldwide, and its
prevalence is rapidly increasing due to extended lifespans. Among the increasing number of …

Throughout the body, lymphatic fluid movement supports critical functions including
clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …

Tau-mediated neurodegeneration is a hallmark of Alzheimer's disease. Primary tauopathies
are characterized by pathological tau accumulation and neuronal and synaptic loss …

Alzheimer's disease (AD) is a fatal progressive neurodegenerative disease. Despite
tremendous research efforts to understand this complex disease, the exact pathophysiology …

Neurodegenerative diseases are characterized by neuronal impairment and loss of function,
and with the major shared histopathological hallmarks of misfolding and aggregation of …

The APOE gene alleles modify human aging and the response to the diet at many levels
with diverse pleotropic effects from gut to brain. To understand the interactions of APOE …

The innate immune system in the central nervous system (CNS) is mainly represented by
specialized tissue‐resident macrophages, called microglia. In the past years, various …

Alzheimer's disease (AD) is the most common cause of dementia. Epidemiological studies
show the association between AD and type 2 diabetes (T2DM), although the mechanisms …

Increasing evidence gives support for the idea that extra-neuronal factors may affect brain
physiology and its predisposition to neurodegenerative diseases. Epidemiological and …

Historically, females have been underrepresented in biological research. With increased
interest in the gut microbiome and the gut-brain axis, it is important for researchers to pursue …