This article reviews the past and current statuses of time-domain near-infrared spectroscopy
(TD-NIRS) and imaging. Although time-domain technology is not yet widely employed due to …

Tissue optics education can use several open-source tools available online. Even though
these tools can be accessed by a broad student population, education environments …

Numerical modeling of light propagation in random media has been an important issue for
biomedical imaging, including diffuse optical tomography (DOT). For high resolution DOT …

The third-order simplified harmonic spherical approximation (SP 3) and diffusion
approximation (DA) equations have been widely used in the three-dimensional (3D) whole …

We developed a new parallel computational method for solving fluorescence and elastically
scattered light propagation through a biological tissue illuminated by a collimated incident …

Aiming at the limitations of the simplified spherical harmonics approximation (SP N) and
diffusion equation (DE) in describing the light propagation in tissues, a hybrid simplified …

Modeling light propagation in the whole body is essential and necessary for optical imaging.
However, non-scattering, low-scattering and high absorption regions commonly exist in …

Objective: The existence of void regions and the complexity of structural heterogeneity and
optical specificity are two challenges encountered in three-dimensional (3-D) optical …

Optical tomography is a powerful tool for preclinical and clinical biomedical research, which
enables quantitative observation and precise localization of regions of interest within …

Optical imaging is an emerging technology capable of qualitatively and quantitatively
observing life processes at the cellular or molecular level and plays a significant role in …