Trauma-induced coagulopathy
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
How to manage coagulopathies in critically ill patients
J Helms, T Iba, JM Connors, S Gando, M Levi… - Intensive care …, 2023 - Springer
Coagulopathy is a severe and frequent complication in critically ill patients, for which the
pathogenesis and presentation may be variable depending on the underlying disease …
pathogenesis and presentation may be variable depending on the underlying disease …
Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised …
N Crombie, HA Doughty, JRB Bishop… - The Lancet …, 2022 - thelancet.com
Background Time to treatment matters in traumatic haemorrhage but the optimal prehospital
use of blood in major trauma remains uncertain. We investigated whether use of packed red …
use of blood in major trauma remains uncertain. We investigated whether use of packed red …
Association of whole blood with survival among patients presenting with severe hemorrhage in US and Canadian adult civilian trauma centers
Importance Whole-blood (WB) resuscitation has gained renewed interest among civilian
trauma centers. However, there remains insufficient evidence that WB as an adjunct to …
trauma centers. However, there remains insufficient evidence that WB as an adjunct to …
Management and challenges of severe traumatic brain injury
S Rakhit, MF Nordness, SR Lombardo… - … in respiratory and …, 2021 - thieme-connect.com
Traumatic brain injury (TBI) is the leading cause of death and disability in trauma patients,
and can be classified into mild, moderate, and severe by the Glasgow coma scale (GCS) …
and can be classified into mild, moderate, and severe by the Glasgow coma scale (GCS) …
WSES consensus conference guidelines: monitoring and management of severe adult traumatic brain injury patients with polytrauma in the first 24 hours
The acute phase management of patients with severe traumatic brain injury (TBI) and
polytrauma represents a major challenge. Guidelines for the care of these complex patients …
polytrauma represents a major challenge. Guidelines for the care of these complex patients …
17α-Ethinyl estradiol-3-sulfate increases survival and hemodynamic functioning in a large animal model of combined traumatic brain injury and hemorrhagic shock: a …
Background Traumatic brain injury (TBI) and severe blood loss resulting in hemorrhagic
shock (HS) represent leading causes of trauma-induced mortality, especially when co …
shock (HS) represent leading causes of trauma-induced mortality, especially when co …
Cryoprecipitate transfusion in trauma patients attenuates hyperfibrinolysis and restores normal clot structure and stability: Results from a laboratory sub-study of the …
Background Fibrinogen is the first coagulation protein to reach critical levels during
traumatic haemorrhage. This laboratory study compares paired plasma samples pre-and …
traumatic haemorrhage. This laboratory study compares paired plasma samples pre-and …
Role of fibrinogen in trauma-induced coagulopathy
BACKGROUND: Fibrinogen is the first coagulation factor to decrease after massive
hemorrhage. European massive transfusion guidelines recommend early repletion of …
hemorrhage. European massive transfusion guidelines recommend early repletion of …
Outcomes after ultramassive transfusion in the modern era: an Eastern Association for the Surgery of Trauma multicenter study
ZA Matthay, ZJ Hellmann, RA Callcut… - Journal of Trauma …, 2021 - journals.lww.com
BACKGROUND Despite the widespread institution of modern massive transfusion protocols
with balanced blood product ratios, survival for patients with traumatic hemorrhage receiving …
with balanced blood product ratios, survival for patients with traumatic hemorrhage receiving …