Tailoring the treatment of inflammatory rheumatic diseases by a better stratification and characterization of the clinical patient heterogeneity. Findings from a …

P Ruscitti, Y Allanore, C Baldini, G Barilaro… - Autoimmunity …, 2024 - Elsevier
Inflammatory rheumatic diseases are different pathologic conditions associated with a
deregulated immune response, codified along a spectrum of disorders, with …

Assessing the potential of epigenetic targets as biomarkers in the diagnosis and treatment of rheumatoid arthritis

N Nair, AG Wilson - Expert Review of Clinical Immunology, 2023 - Taylor & Francis
Introduction Although there are gold-standard diagnostic guidelines and effective treatments
to slow the disease progression of rheumatoid arthritis (RA), approximately 40% of patients …

Organizational justice and long-term metabolic trajectories: a 25-year follow-up of the Whitehall II cohort

TV Varga, T Xu, M Kivimäki, AJ Mehta… - The Journal of …, 2022 - academic.oup.com
Context Organizational justice has been linked to lower risk of several chronic conditions
among employees, but less is known about the long-term mechanisms underlying this risk …

Real-world sarilumab use and rule testing to predict treatment response in patients with rheumatoid arthritis: Findings from the rise registry

JR Curtis, H Yun, L Chen, SS Ford… - Rheumatology and …, 2023 - Springer
Introduction Clinical trial findings may not be generalizable to routine practice. This study
evaluated sarilumab effectiveness in patients with rheumatoid arthritis (RA) and tested the …

Interleukin‐6 neutralization and regulatory T cells are additive in chondroprotection from IL‐1β‐induced inflammation

LE Keller, ED Tait Wojno, L Begum… - Journal of Orthopaedic …, 2023 - Wiley Online Library
Anti‐inflammatory Regulatory T cells (Tregs) are enriched in the joints of patients with
osteoarthritis (OA) compared to healthy joints. Tregs maintain homeostasis through …

Distinct long-term disease activity trajectories differentiate early on treatment with etanercept in both rheumatoid arthritis and spondylarthritis patients: a prospective …

I Flouri, P Goutakoli, A Repa, A Bertsias… - Rheumatology …, 2024 - Springer
To characterize disease activity trajectories and compare long-term drug retention between
rheumatoid (RA) and spondylarthritis (SpA) patients initiating tumor necrosis factor inhibitor …

Exploratory analysis to investigate the diseases of polymyalgia rheumatica, giant cell arteritis and rheumatoid arthritis

JE Manning - 2023 - etheses.bham.ac.uk
This thesis uses exploratory forms of analysis to investigate three inflammatory, autoimmune
rheumatic diseases; polymyalgia rheumatica (PMR), giant cell arteritis (GCA) and …