The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …

The burden of diabetic foot disease (DFD) is expected to increase in the future. The
incidence of DFD is still rising due to the high prevalence of DFD predisposing factors. DFD …

Background: Revision of the guidelines on the use of skin biopsy in the diagnosis of
peripheral neuropathy, published in 2005, has become appropriate owing to publication of …

Objective: Small nerve fiber neuropathy (SFN) often occurs without apparent cause, but no
systematic genetic studies have been performed in patients with idiopathic SFN (I‐SFN). We …

The diagnostic reliability of skin biopsy in small fiber neuropathy depends on the availability
of normative reference values. We performed a multicenter study to assess the normative …

Small fibre neuropathy (SFN), a condition dominated by neuropathic pain, is frequently
encountered in clinical practise either as prevalent manifestation of more diffuse neuropathy …

Chemotherapy induced peripheral neuropathy (CIPN) is a type of neuropathic pain that is a
major dose-limiting side-effect of potentially curative cancer chemotherapy treatment …

Diabetic neuropathy is not a single entity but rather a number of different syndromes, each
with a range of clinical and subclinical manifestations. According to the San Antonio …

Skin biopsy has become a widely used tool to investigate small calibre sensory nerves
including somatic unmyelinated intraepidermal nerve fibres (IENF), dermal myelinated nerve …

Surrogate markers of diabetic neuropathy are being actively sought to facilitate the
diagnosis, measure the progression, and assess the benefits of therapeutic intervention in …