[HTML][HTML] Linking pollution and cancer in aquatic environments: A review
Due to the interconnectedness of aquatic ecosystems through the highly effective marine
and atmospheric transport routes, all aquatic ecosystems are potentially vulnerable to …
and atmospheric transport routes, all aquatic ecosystems are potentially vulnerable to …
Towards a unified open access dataset of molecular interactions
Abstract The International Molecular Exchange (IMEx) Consortium provides scientists with a
single body of experimentally verified protein interactions curated in rich contextual detail to …
single body of experimentally verified protein interactions curated in rich contextual detail to …
[HTML][HTML] Information fusion as an integrative cross-cutting enabler to achieve robust, explainable, and trustworthy medical artificial intelligence
Medical artificial intelligence (AI) systems have been remarkably successful, even
outperforming human performance at certain tasks. There is no doubt that AI is important to …
outperforming human performance at certain tasks. There is no doubt that AI is important to …
Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity
O Cabral-Marques, G Halpert, LF Schimke… - Nature …, 2022 - nature.com
COVID-19 shares the feature of autoantibody production with systemic autoimmune
diseases. In order to understand the role of these immune globulins in the pathogenesis of …
diseases. In order to understand the role of these immune globulins in the pathogenesis of …
Learning interpretable cellular and gene signature embeddings from single-cell transcriptomic data
The advent of single-cell RNA sequencing (scRNA-seq) technologies has revolutionized
transcriptomic studies. However, large-scale integrative analysis of scRNA-seq data remains …
transcriptomic studies. However, large-scale integrative analysis of scRNA-seq data remains …
[HTML][HTML] Dysregulated autoantibodies targeting vaso-and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity
F Sotzny, IS Filgueiras, C Kedor, H Freitag… - Frontiers in …, 2022 - frontiersin.org
Most patients with Post COVID Syndrome (PCS) present with a plethora of symptoms without
clear evidence of organ dysfunction. A subset of them fulfills diagnostic criteria of myalgic …
clear evidence of organ dysfunction. A subset of them fulfills diagnostic criteria of myalgic …
Nine quick tips for pathway enrichment analysis
Pathway enrichment analysis (PEA) is a computational biology method that identifies
biological functions that are overrepresented in a group of genes more than would be …
biological functions that are overrepresented in a group of genes more than would be …
Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease
Spondyloarthritis (SpA), a type 3 immunity-mediated inflammatory arthritis, is a systemic
rheumatic disease that primarily affects the joints, spine, gut, skin, and eyes. Macrophage …
rheumatic disease that primarily affects the joints, spine, gut, skin, and eyes. Macrophage …
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
SH Lim, J Snider, L Birimberg‐Schwartz… - Molecular systems …, 2022 - embopress.org
Abstract Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a chloride and
bicarbonate channel in secretory epithelia with a critical role in maintaining fluid …
bicarbonate channel in secretory epithelia with a critical role in maintaining fluid …
Circulating microRNAs differentiate fast-progressing from slow-progressing and non-progressing knee osteoarthritis in the Osteoarthritis Initiative cohort
Introduction: The objective of this study is to identify circulating microRNAs that distinguish
fast-progressing radiographic knee osteoarthritis (OA) in the Osteoarthritis Initiative cohort by …
fast-progressing radiographic knee osteoarthritis (OA) in the Osteoarthritis Initiative cohort by …