Means and methods for influencing the stability of antibody producing cells
The invention provides a method for influencing the stability of an antibody producing cell,
comprising directly or indi rectly influencing the amount of BCL6 and/or Blimp 1 expression …
comprising directly or indi rectly influencing the amount of BCL6 and/or Blimp 1 expression …
Means and methods for producing high affinity antibodies
T Beaumont, H Spits, MJ Kwakkenbos… - US Patent …, 2016 - Google Patents
US9273118B2 - Means and methods for producing high affinity antibodies - Google Patents
US9273118B2 - Means and methods for producing high affinity antibodies - Google Patents …
US9273118B2 - Means and methods for producing high affinity antibodies - Google Patents …
Means and methods for influencing the stability of cells
H Spits - US Patent 9,005,974, 2015 - Google Patents
EP 1627.563 2, 2006 EP 1627 S63 A 2, 2006 GB 2398.783 9, 2004 WO WO 89, 08146 9,
1989 WO WO94, 08004 4f1994 WO WO94, 17086 8, 1994 WO 9427426 A1 12, 1994 WO …
1989 WO WO94, 08004 4f1994 WO WO94, 17086 8, 1994 WO 9427426 A1 12, 1994 WO …
Affinity maturated T cell receptors and use thereof
L Eisenbach, Y Gozlan, E Tzehoval - US Patent 10,081,663, 2018 - Google Patents
The present invention relates to methods and systems for increasing the affinity of a T cell
receptor (TCR) to its ligand by subjecting the TCR gene to somatic hypermutation. The …
receptor (TCR) to its ligand by subjecting the TCR gene to somatic hypermutation. The …
Means and methods for influencing the stability of antibody producing cells
The invention provides a method for influencing the stability of an antibody producing cell,
comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression …
comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression …
Means and methods for producing stable antibodies
MJ Kwakkenbos, K Wagner, AQ Bakker - US Patent 10,611,829, 2020 - Google Patents
US10611829B2 - Means and methods for producing stable antibodies - Google Patents
US10611829B2 - Means and methods for producing stable antibodies - Google Patents …
US10611829B2 - Means and methods for producing stable antibodies - Google Patents …
Hyperactive AID/APOBEC and hmC dominant TET enzymes
R Kohli, E Schutsky, MY Liu - US Patent 11,634,700, 2023 - Google Patents
cytosine modifying enzymes provide an added layer of diversity to the genome. Cytosine
can be modified by deamination, oxidation and methylation, with each of these modifications …
can be modified by deamination, oxidation and methylation, with each of these modifications …
Affinity maturated T cell receptors and use thereof
RL Eisenbach, Y Gozlan, E Tzehoval - US Patent 11,273,178, 2022 - Google Patents
The present invention relates to methods and systems for increasing the affinity of a T cell
receptor (TCR) to its ligand by subjecting the TCR gene to somatic hypermutation. The …
receptor (TCR) to its ligand by subjecting the TCR gene to somatic hypermutation. The …
Hyperactive AID/APOBEC and hmC dominant TET enzymes
RM Kohli, E Schutsky, MY Liu - US Patent 10,961,525, 2021 - Google Patents
2020-03-10 Assigned to THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
reassignment THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ASSIGNMENT …
reassignment THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ASSIGNMENT …
Means and methods for influencing the stability of cells
H Spits - US Patent 10,774,308, 2020 - Google Patents
The invention provides a method for influencing the stability of an antibody producing cell,
comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression …
comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression …