Normal tension glaucoma: review of current understanding and mechanisms of the pathogenesis

HE Killer, A Pircher - Eye, 2018 - nature.com
Normal tension glaucoma (NTG) is an exception in the “glaucoma family” where the major
risk factor, increased intraocular pressure, is missing. If not increased intraocular pressure …

Normal‑tension glaucoma: Pathogenesis and genetics

A Trivli, I Koliarakis, C Terzidou… - Experimental and …, 2019 - spandidos-publications.com
Normal‑tension glaucoma (NTG) is a multifactorial optic neuropathy which, similar to open‑
angle glaucomas, is characterized by progressive retinal ganglion cell death and …

Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma care

J Zhang, K Kim, HJ Kim, D Meyer, W Park… - Nature …, 2022 - nature.com
Continuous monitoring of intraocular pressure, particularly during sleep, remains a grand
challenge in glaucoma care. Here we introduce a class of smart soft contact lenses …

Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation

M Hou, Z Shao, S Zhang, X Liu, P Fan, M Jiang… - Cell Death & …, 2022 - nature.com
Retinal ganglion cells (RGCs) axons are the signal carriers of visual information between
retina and brain. Therefore, they play one of the important roles affected in many optic …

Brain physiological response and adaptation during spaceflight

K Marshall-Goebel, R Damani, EM Bershad - Neurosurgery, 2019 - journals.lww.com
More than half of astronauts returning from long-duration missions on the International
Space Station present with neuro-ocular structural and/or functional changes, including optic …

Intracranial and intraocular pressure at the lamina cribrosa: gradient effects

G Jóhannesson, A Eklund, C Lindén - Current neurology and …, 2018 - Springer
Purpose of Review A pressure difference between the intraocular and intracranial
compartments at the site of the lamina cribrosa has been hypothesized to have a …

Finite element modeling of effects of tissue property variation on human optic nerve tethering during adduction

J Park, A Shin, JL Demer - Scientific reports, 2022 - nature.com
Tractional tethering by the optic nerve (ON) on the eye as it rotates towards the midline in
adduction is a significant ocular mechanical load and has been suggested as a cause of ON …

The role of intracranial pressure in glaucoma and therapeutic implications

AJ Baneke, J Aubry, AC Viswanathan, GT Plant - Eye, 2020 - nature.com
Despite glaucoma being the second leading cause of blindness globally, its pathogenesis
remains incompletely understood. Although intraocular pressure (IOP) contributes to …

Noninvasive methods to monitor intracranial pressure

M Dattilo - Current Opinion in Neurology, 2023 - journals.lww.com
Although invasive methods remain the mainstay for ICP determination and monitoring,
several noninvasive biomarkers have shown promise to quantitatively assess and monitor …

Current concepts of cerebrospinal fluid dynamics and the translaminar cribrosa pressure gradient: a paradigm of optic disk disease

KC Liu, D Fleischman, AG Lee, HE Killer, JJ Chen… - Survey of …, 2020 - Elsevier
Modern advances in measuring and studying cerebrospinal fluid dynamics have furthered
our understanding of intracranial pressure and its pathophysiological effects on the eye. In …